Doshi KA - Search Results

1

Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress.

Doshi KA, Trotta R, Natarajan K, Rassool FV, Tron AE, Huszar D, Perrotti D, Baer MR. Doshi KA, et al. Oncotarget. 2016 Jul 26;7(30):48280-48295. doi: 10.18632/oncotarget.10209. Oncotarget. 2016. PMID: 27374090 Free PMC article.

2

Concurrent Inhibition of Pim and FLT3 Kinases Enhances Apoptosis of FLT3-ITD Acute Myeloid Leukemia Cells through Increased Mcl-1 Proteasomal Degradation.

Kapoor S, Natarajan K, Baldwin PR, Doshi KA, Lapidus RG, Mathias TJ, Scarpa M, Trotta R, Davila E, Kraus M, Huszar D, Tron AE, Perrotti D, Baer MR. Kapoor S, et al. Among authors: doshi ka. Clin Cancer Res. 2018 Jan 1;24(1):234-247. doi: 10.1158/1078-0432.CCR-17-1629. Epub 2017 Oct 26. Clin Cancer Res. 2018. PMID: 29074603 Free PMC article.

3

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication.

Scarpa M, Kapoor S, Tvedte ES, Doshi KA, Zou YS, Singh P, Lee JK, Chatterjee A, Ali MKM, Bromley RE, Hotopp JCD, Rassool FV, Baer MR. Scarpa M, et al. Among authors: doshi ka. Oncotarget. 2021 Aug 31;12(18):1763-1779. doi: 10.18632/oncotarget.28042. eCollection 2021 Aug 31. Oncotarget. 2021. PMID: 34504649 Free PMC article.

4

The FLT3 and PDGFR inhibitor crenolanib is a substrate of the multidrug resistance protein ABCB1 but does not inhibit transport function at pharmacologically relevant concentrations.

Mathias TJ, Natarajan K, Shukla S, Doshi KA, Singh ZN, Ambudkar SV, Baer MR. Mathias TJ, et al. Among authors: doshi ka. Invest New Drugs. 2015 Apr;33(2):300-9. doi: 10.1007/s10637-015-0205-y. Epub 2015 Jan 20. Invest New Drugs. 2015. PMID: 25597754 Free PMC article.

5

Uncovering low-dimensional, miR-based signatures of acute myeloid and lymphoblastic leukemias with a machine-learning-driven network approach.

Candia J, Cherukuri S, Guo Y, Doshi KA, Banavar JR, Civin CI, Losert W. Candia J, et al. Among authors: doshi ka. Converg Sci Phys Oncol. 2015 Dec;1(2):025002. doi: 10.1088/2057-1739/1/2/025002. Epub 2015 Dec 21. Converg Sci Phys Oncol. 2015. PMID: 27274862 Free PMC article.

6

Type-I interferon signaling is essential for robust metronomic chemo-immunogenic tumor regression in murine breast cancer.

Vergato C, Doshi KA, Roblyer D, Waxman DJ. Vergato C, et al. Among authors: doshi ka. Cancer Res Commun. 2022 Apr;2(4):246-257. doi: 10.1158/2767-9764.crc-21-0148. Epub 2022 Apr 22. Cancer Res Commun. 2022. PMID: 36187936 Free PMC article.

7

Transfusion requirement prediction score for patients undergoing cardiac surgery: An experience from a tertiary care set-up from South India.

Doshi KA, Shastry S, Pai VB. Doshi KA, et al. Transfus Med. 2021 Aug;31(4):243-249. doi: 10.1111/tme.12774. Epub 2021 Apr 25. Transfus Med. 2021. PMID: 33899279

8

Estimating drug potency in the competitive target mediated drug disposition (TMDD) system when the endogenous ligand is included.

Alaybeyoglu B, Cheng HWJ, Doshi KA, Makani V, Stein AM. Alaybeyoglu B, et al. Among authors: doshi ka. J Pharmacokinet Pharmacodyn. 2021 Aug;48(4):447-464. doi: 10.1007/s10928-020-09734-9. Epub 2021 Feb 8. J Pharmacokinet Pharmacodyn. 2021. PMID: 33558979

9

Impact of stored red cells on clinical outcome in critically ill.

Shivhare A, Shastry S, Murugesan M, Doshi KA, Baliga BP. Shivhare A, et al. Among authors: doshi ka. Asian J Transfus Sci. 2019 Jan-Jun;13(1):17-22. doi: 10.4103/ajts.AJTS_76_18. Asian J Transfus Sci. 2019. PMID: 31360005 Free PMC article.

10

Use of infusion pump for intrauterine transfusion: An effective hands-free transfusion circuit.

Shastry S, Doshi KA, Kankula VR, Guduri PR. Shastry S, et al. Among authors: doshi ka. Asian J Transfus Sci. 2018 Jul-Dec;12(2):97-98. doi: 10.4103/ajts.AJTS_91_17. Asian J Transfus Sci. 2018. PMID: 30692791 Free PMC article. No abstract available.

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