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Page 1
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Lampropoulou V, Sergushichev A, Bambouskova M, Nair S, Vincent EE, Loginicheva E, Cervantes-Barragan L, Ma X, Huang SC, Griss T, Weinheimer CJ, Khader S, Randolph GJ, Pearce EJ, Jones RG, Diwan A, Diamond MS, Artyomov MN. Lampropoulou V, et al. Among authors: pearce ej. Cell Metab. 2016 Jul 12;24(1):158-66. doi: 10.1016/j.cmet.2016.06.004. Epub 2016 Jun 30. Cell Metab. 2016. PMID: 27374498 Free PMC article.
Th2 responses in schistosomiasis.
Fairfax K, Nascimento M, Huang SC, Everts B, Pearce EJ. Fairfax K, et al. Among authors: pearce ej. Semin Immunopathol. 2012 Nov;34(6):863-71. doi: 10.1007/s00281-012-0354-4. Epub 2012 Nov 9. Semin Immunopathol. 2012. PMID: 23139101 Review.
Posttranscriptional control of T cell effector function by aerobic glycolysis.
Chang CH, Curtis JD, Maggi LB Jr, Faubert B, Villarino AV, O'Sullivan D, Huang SC, van der Windt GJ, Blagih J, Qiu J, Weber JD, Pearce EJ, Jones RG, Pearce EL. Chang CH, et al. Among authors: pearce ej, pearce el. Cell. 2013 Jun 6;153(6):1239-51. doi: 10.1016/j.cell.2013.05.016. Cell. 2013. PMID: 23746840 Free PMC article.
CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability.
van der Windt GJ, O'Sullivan D, Everts B, Huang SC, Buck MD, Curtis JD, Chang CH, Smith AM, Ai T, Faubert B, Jones RG, Pearce EJ, Pearce EL. van der Windt GJ, et al. Among authors: pearce ej, pearce el. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14336-41. doi: 10.1073/pnas.1221740110. Epub 2013 Aug 12. Proc Natl Acad Sci U S A. 2013. PMID: 23940348 Free PMC article.
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.
Everts B, Amiel E, Huang SC, Smith AM, Chang CH, Lam WY, Redmann V, Freitas TC, Blagih J, van der Windt GJ, Artyomov MN, Jones RG, Pearce EL, Pearce EJ. Everts B, et al. Among authors: pearce ej, pearce el. Nat Immunol. 2014 Apr;15(4):323-32. doi: 10.1038/ni.2833. Epub 2014 Feb 23. Nat Immunol. 2014. PMID: 24562310 Free PMC article.
Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter.
Reese TA, Wakeman BS, Choi HS, Hufford MM, Huang SC, Zhang X, Buck MD, Jezewski A, Kambal A, Liu CY, Goel G, Murray PJ, Xavier RJ, Kaplan MH, Renne R, Speck SH, Artyomov MN, Pearce EJ, Virgin HW. Reese TA, et al. Among authors: pearce ej. Science. 2014 Aug 1;345(6196):573-7. doi: 10.1126/science.1254517. Epub 2014 Jun 26. Science. 2014. PMID: 24968940 Free PMC article.
Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.
O'Sullivan D, van der Windt GJ, Huang SC, Curtis JD, Chang CH, Buck MD, Qiu J, Smith AM, Lam WY, DiPlato LM, Hsu FF, Birnbaum MJ, Pearce EJ, Pearce EL. O'Sullivan D, et al. Among authors: pearce ej, pearce el. Immunity. 2014 Jul 17;41(1):75-88. doi: 10.1016/j.immuni.2014.06.005. Epub 2014 Jul 4. Immunity. 2014. PMID: 25001241 Free PMC article.
256 results