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OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models.
Berenguer-Daizé C, Astorgues-Xerri L, Odore E, Cayol M, Cvitkovic E, Noel K, Bekradda M, MacKenzie S, Rezai K, Lokiec F, Riveiro ME, Ouafik L. Berenguer-Daizé C, et al. Among authors: ouafik l. Int J Cancer. 2016 Nov 1;139(9):2047-55. doi: 10.1002/ijc.30256. Epub 2016 Jul 30. Int J Cancer. 2016. PMID: 27388964
Expression and role of adrenomedullin in renal tumors and value of its mRNA levels as prognostic factor in clear-cell renal carcinoma.
Deville JL, Bartoli C, Berenguer C, Fernandez-Sauze S, Kaafarani I, Delfino C, Fina F, Salas S, Muracciole X, Mancini J, Lechevallier E, Martin PM, Figarella-Branger D, Ouafik L, Daniel L. Deville JL, et al. Among authors: ouafik l. Int J Cancer. 2009 Nov 15;125(10):2307-15. doi: 10.1002/ijc.24568. Int J Cancer. 2009. PMID: 19610056
Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo.
Nouguerède E, Berenguer C, Garcia S, Bennani B, Delfino C, Nanni I, Dahan L, Gasmi M, Seitz JF, Martin PM, Ouafik L. Nouguerède E, et al. Among authors: ouafik l. Cancer Med. 2013 Apr;2(2):196-207. doi: 10.1002/cam4.51. Epub 2013 Jan 29. Cancer Med. 2013. Retraction in: Cancer Med. 2024 Sep;13(18):e70172. doi: 10.1002/cam4.70172 PMID: 23634287 Free PMC article. Retracted.
Adrenomedullin blockade suppresses growth of human hormone-independent prostate tumor xenograft in mice.
Berenguer-Daizé C, Boudouresque F, Bastide C, Tounsi A, Benyahia Z, Acunzo J, Dussault N, Delfino C, Baeza N, Daniel L, Cayol M, Rossi D, El Battari A, Bertin D, Mabrouk K, Martin PM, Ouafik L. Berenguer-Daizé C, et al. Among authors: ouafik l. Clin Cancer Res. 2013 Nov 15;19(22):6138-50. doi: 10.1158/1078-0432.CCR-13-0691. Epub 2013 Oct 7. Clin Cancer Res. 2013. PMID: 24100627
Differential expression of miR200a-3p and miR21 in grade II-III and grade IV gliomas: evidence that miR200a-3p is regulated by O⁶-methylguanine methyltransferase and promotes temozolomide responsiveness.
Berthois Y, Delfino C, Metellus P, Fina F, Nanni-Metellus I, Al Aswy H, Pirisi V, Ouafik L, Boudouresque F. Berthois Y, et al. Among authors: ouafik l. Cancer Biol Ther. 2014 Jul;15(7):938-50. doi: 10.4161/cbt.28920. Epub 2014 Apr 22. Cancer Biol Ther. 2014. PMID: 24755707 Free PMC article.
Adrenomedullin blockade induces regression of tumor neovessels through interference with vascular endothelial-cadherin signalling.
Khalfaoui-Bendriss G, Dussault N, Fernandez-Sauze S, Berenguer-Daizé C, Sigaud R, Delfino C, Cayol M, Metellus P, Chinot O, Mabrouk K, Martin PM, Ouafik L. Khalfaoui-Bendriss G, et al. Among authors: ouafik l. Oncotarget. 2015 Apr 10;6(10):7536-53. doi: 10.18632/oncotarget.3167. Oncotarget. 2015. PMID: 25924235 Free PMC article.
Functional Analysis of the Adrenomedullin Pathway in Malignant Pleural Mesothelioma.
Greillier L, Tounsi A, Berenguer-Daizé C, Dussault N, Delfino C, Benyahia Z, Cayol M, Mabrouk K, Garcia S, Martin PM, Barlesi F, Ouafik L. Greillier L, et al. Among authors: ouafik l. J Thorac Oncol. 2016 Jan;11(1):94-107. doi: 10.1016/j.jtho.2015.09.004. J Thorac Oncol. 2016. PMID: 26762744 Free article.
Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer.
Civenni G, Bosotti R, Timpanaro A, Vàzquez R, Merulla J, Pandit S, Rossi S, Albino D, Allegrini S, Mitra A, Mapelli SN, Vierling L, Giurdanella M, Marchetti M, Paganoni A, Rinaldi A, Losa M, Mira-Catò E, D'Antuono R, Morone D, Rezai K, D'Ambrosio G, Ouafik L, Mackenzie S, Riveiro ME, Cvitkovic E, Carbone GM, Catapano CV. Civenni G, et al. Among authors: ouafik l. Cell Metab. 2019 Aug 6;30(2):303-318.e6. doi: 10.1016/j.cmet.2019.05.004. Epub 2019 May 23. Cell Metab. 2019. PMID: 31130467 Free article.
165 results