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Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770.
Gentzsch M, Ren HY, Houck SA, Quinney NL, Cholon DM, Sopha P, Chaudhry IG, Das J, Dokholyan NV, Randell SH, Cyr DM. Gentzsch M, et al. Among authors: randell sh. Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L550-9. doi: 10.1152/ajplung.00186.2016. Epub 2016 Jul 8. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27402691 Free PMC article.
Cytokine secretion by cystic fibrosis airway epithelial cells.
Becker MN, Sauer MS, Muhlebach MS, Hirsh AJ, Wu Q, Verghese MW, Randell SH. Becker MN, et al. Among authors: randell sh. Am J Respir Crit Care Med. 2004 Mar 1;169(5):645-53. doi: 10.1164/rccm.200207-765OC. Epub 2003 Dec 11. Am J Respir Crit Care Med. 2004. PMID: 14670800
Transcellular thiocyanate transport by human airway epithelia.
Fragoso MA, Fernandez V, Forteza R, Randell SH, Salathe M, Conner GE. Fragoso MA, et al. Among authors: randell sh. J Physiol. 2004 Nov 15;561(Pt 1):183-94. doi: 10.1113/jphysiol.2004.071548. Epub 2004 Sep 2. J Physiol. 2004. PMID: 15345749 Free PMC article.
Novel human bronchial epithelial cell lines for cystic fibrosis research.
Fulcher ML, Gabriel SE, Olsen JC, Tatreau JR, Gentzsch M, Livanos E, Saavedra MT, Salmon P, Randell SH. Fulcher ML, et al. Among authors: randell sh. Am J Physiol Lung Cell Mol Physiol. 2009 Jan;296(1):L82-91. doi: 10.1152/ajplung.90314.2008. Epub 2008 Oct 31. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 18978040 Free PMC article.
Loss of Cftr function exacerbates the phenotype of Na(+) hyperabsorption in murine airways.
Livraghi-Butrico A, Kelly EJ, Wilkinson KJ, Rogers TD, Gilmore RC, Harkema JR, Randell SH, Boucher RC, O'Neal WK, Grubb BR. Livraghi-Butrico A, et al. Among authors: randell sh. Am J Physiol Lung Cell Mol Physiol. 2013 Apr 1;304(7):L469-80. doi: 10.1152/ajplung.00150.2012. Epub 2013 Feb 1. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 23377346 Free PMC article.
The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia.
Turner MJ, Matthes E, Billet A, Ferguson AJ, Thomas DY, Randell SH, Ostrowski LE, Abbott-Banner K, Hanrahan JW. Turner MJ, et al. Among authors: randell sh. Am J Physiol Lung Cell Mol Physiol. 2016 Jan 1;310(1):L59-70. doi: 10.1152/ajplung.00324.2015. Epub 2015 Nov 6. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 26545902 Free article.
247 results