Stiborová M - Search Results

1

NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene.

Stiborová M, Indra R, Moserová M, Frei E, Schmeiser HH, Kopka K, Phillips DH, Arlt VM. Stiborová M, et al. Chem Res Toxicol. 2016 Aug 15;29(8):1325-34. doi: 10.1021/acs.chemrestox.6b00143. Epub 2016 Jul 20. Chem Res Toxicol. 2016. PMID: 27404282 Free PMC article.

2

Covalent binding of the anticancer drug ellipticine to DNA in V79 cells transfected with human cytochrome P450 enzymes.

Frei E, Bieler CA, Arlt VM, Wiessler M, Stiborová M. Frei E, et al. Among authors: stiborova m. Biochem Pharmacol. 2002 Jul 15;64(2):289-95. doi: 10.1016/s0006-2952(02)01072-9. Biochem Pharmacol. 2002. PMID: 12123750

3

Rat microsomes activating the anticancer drug ellipticine to species covalently binding to deoxyguanosine in DNA are a suitable model mimicking ellipticine bioactivation in humans.

Stiborová M, Stiborová-Rupertová M, Borek-Dohalská L, Wiessler M, Frei E. Stiborová M, et al. Among authors: stiborova rupertova m. Chem Res Toxicol. 2003 Jan;16(1):38-47. doi: 10.1021/tx0200818. Chem Res Toxicol. 2003. PMID: 12693029

4

Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.

Arlt VM, Stiborova M, Hewer A, Schmeiser HH, Phillips DH. Arlt VM, et al. Among authors: stiborova m. Cancer Res. 2003 Jun 1;63(11):2752-61. Cancer Res. 2003. PMID: 12782579

5

Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its oxidative detoxication by human cytochromes P450.

Miksanová M, Sulc M, Rýdlová H, Schmeiser HH, Frei E, Stiborová M. Miksanová M, et al. Among authors: stiborova m. Chem Res Toxicol. 2004 May;17(5):663-71. doi: 10.1021/tx0499721. Chem Res Toxicol. 2004. PMID: 15144223

6

3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.

Arlt VM, Hewer A, Sorg BL, Schmeiser HH, Phillips DH, Stiborova M. Arlt VM, et al. Among authors: stiborova m. Chem Res Toxicol. 2004 Aug;17(8):1092-101. doi: 10.1021/tx049912v. Chem Res Toxicol. 2004. PMID: 15310241

7

Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.

Stiborová M, Frei E, Hodek P, Wiessler M, Schmeiser HH. Stiborová M, et al. Int J Cancer. 2005 Jan 10;113(2):189-97. doi: 10.1002/ijc.20564. Int J Cancer. 2005. PMID: 15386410

8

The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen.

Stiborová M, Sopko B, Hodek P, Frei E, Schmeiser HH, Hudecek J. Stiborová M, et al. Cancer Lett. 2005 Nov 18;229(2):193-204. doi: 10.1016/j.canlet.2005.06.038. Epub 2005 Aug 24. Cancer Lett. 2005. PMID: 16125300

9

Modulation of CYP1A1-mediated oxidation of carcinogenic azo dye Sudan I and its binding to DNA by cytochrome b5.

Stiborová M, Martínek V, Schmeiser HH, Frei E. Stiborová M, et al. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:35-9. Neuro Endocrinol Lett. 2006. PMID: 17159775

10

Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: studies with the hepatic NADPH:cytochrome P450 reductase null mouse.

Stiborová M, Arlt VM, Henderson CJ, Wolf CR, Kotrbová V, Moserová M, Hudecek J, Phillips DH, Frei E. Stiborová M, et al. Toxicol Appl Pharmacol. 2008 Feb 1;226(3):318-27. doi: 10.1016/j.taap.2007.09.017. Epub 2007 Sep 26. Toxicol Appl Pharmacol. 2008. PMID: 17976674

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