O'Dwyer KM - Search Results

1

Evolution of acute myelogenous leukemia stem cell properties after treatment and progression.

Ho TC, LaMere M, Stevens BM, Ashton JM, Myers JR, O'Dwyer KM, Liesveld JL, Mendler JH, Guzman M, Morrissette JD, Zhao J, Wang ES, Wetzler M, Jordan CT, Becker MW. Ho TC, et al. Blood. 2016 Sep 29;128(13):1671-8. doi: 10.1182/blood-2016-02-695312. Epub 2016 Jul 15. Blood. 2016. PMID: 27421961 Free PMC article.

2

BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.

Lagadinou ED, Sach A, Callahan K, Rossi RM, Neering SJ, Minhajuddin M, Ashton JM, Pei S, Grose V, O'Dwyer KM, Liesveld JL, Brookes PS, Becker MW, Jordan CT. Lagadinou ED, et al. Cell Stem Cell. 2013 Mar 7;12(3):329-41. doi: 10.1016/j.stem.2012.12.013. Epub 2013 Jan 17. Cell Stem Cell. 2013. PMID: 23333149 Free PMC article.

3

Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.

Pei S, Minhajuddin M, Callahan KP, Balys M, Ashton JM, Neering SJ, Lagadinou ED, Corbett C, Ye H, Liesveld JL, O'Dwyer KM, Li Z, Shi L, Greninger P, Settleman J, Benes C, Hagen FK, Munger J, Crooks PA, Becker MW, Jordan CT. Pei S, et al. J Biol Chem. 2013 Nov 22;288(47):33542-33558. doi: 10.1074/jbc.M113.511170. Epub 2013 Oct 2. J Biol Chem. 2013. PMID: 24089526 Free PMC article. Clinical Trial.

4

A phase I study of decitabine and rapamycin in relapsed/refractory AML.

Liesveld JL, O'Dwyer K, Walker A, Becker MW, Ifthikharuddin JJ, Mulford D, Chen R, Bechelli J, Rosell K, Minhajuddin M, Jordan CT, Phillips GL 2nd. Liesveld JL, et al. Leuk Res. 2013 Dec;37(12):1622-7. doi: 10.1016/j.leukres.2013.09.002. Epub 2013 Sep 8. Leuk Res. 2013. PMID: 24138944 Clinical Trial.

5

Discovery of potent parthenolide-based antileukemic agents enabled by late-stage P450-mediated C-H functionalization.

Kolev JN, O'Dwyer KM, Jordan CT, Fasan R. Kolev JN, et al. ACS Chem Biol. 2014 Jan 17;9(1):164-73. doi: 10.1021/cb400626w. Epub 2013 Nov 8. ACS Chem Biol. 2014. PMID: 24206617 Free PMC article.

6

Chemoenzymatic synthesis and antileukemic activity of novel C9- and C14-functionalized parthenolide analogs.

Tyagi V, Alwaseem H, O'Dwyer KM, Ponder J, Li QY, Jordan CT, Fasan R. Tyagi V, et al. Bioorg Med Chem. 2016 Sep 1;24(17):3876-3886. doi: 10.1016/j.bmc.2016.06.028. Epub 2016 Jun 16. Bioorg Med Chem. 2016. PMID: 27396927 Free PMC article.

7

Philadelphia chromosome negative B-cell acute lymphoblastic leukemia in older adults: Current treatment and novel therapies.

O'Dwyer KM, Liesveld JL. O'Dwyer KM, et al. Best Pract Res Clin Haematol. 2017 Sep;30(3):184-192. doi: 10.1016/j.beha.2017.08.001. Epub 2017 Aug 3. Best Pract Res Clin Haematol. 2017. PMID: 29050691 Review.

8

Can we incorporate geriatric assessment in the management of acute lymphoblastic leukemia in older adults?

Loh KP, Liesveld JL, O'Dwyer KM. Loh KP, et al. J Geriatr Oncol. 2018 Jul;9(4):296-301. doi: 10.1016/j.jgo.2018.03.015. Epub 2018 Apr 5. J Geriatr Oncol. 2018. PMID: 29628416 Review.

9

High dose daunorubicin: New standard of care for FLT3 ITD mutant AML.

Wang ES, O'Dwyer K. Wang ES, et al. Leuk Res. 2018 Jun;69:87-88. doi: 10.1016/j.leukres.2018.04.011. Epub 2018 Apr 23. Leuk Res. 2018. PMID: 29705536 No abstract available.

10

Allogeneic Hematopoietic Cell Transplantation for Older Adults with Acute Myeloid Leukemia.

Lipof JJ, Loh KP, O'Dwyer K, Liesveld JL. Lipof JJ, et al. Cancers (Basel). 2018 Jun 4;10(6):179. doi: 10.3390/cancers10060179. Cancers (Basel). 2018. PMID: 29866998 Free PMC article. Review.

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