Skip to main page content
U.S. flag

An official website of the United States government

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Search Results

67 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.
Inoue S, Li WY, Tseng A, Beerman I, Elia AJ, Bendall SC, Lemonnier F, Kron KJ, Cescon DW, Hao Z, Lind EF, Takayama N, Planello AC, Shen SY, Shih AH, Larsen DM, Li Q, Snow BE, Wakeham A, Haight J, Gorrini C, Bassi C, Thu KL, Murakami K, Elford AR, Ueda T, Straley K, Yen KE, Melino G, Cimmino L, Aifantis I, Levine RL, De Carvalho DD, Lupien M, Rossi DJ, Nolan GP, Cairns RA, Mak TW. Inoue S, et al. Among authors: cairns ra. Cancer Cell. 2016 Aug 8;30(2):337-348. doi: 10.1016/j.ccell.2016.05.018. Epub 2016 Jul 14. Cancer Cell. 2016. PMID: 27424808 Free PMC article.
Regulation of cancer cell metabolism.
Cairns RA, Harris IS, Mak TW. Cairns RA, et al. Nat Rev Cancer. 2011 Feb;11(2):85-95. doi: 10.1038/nrc2981. Nat Rev Cancer. 2011. PMID: 21258394 Review.
Cancer cell metabolism.
Cairns RA, Harris I, McCracken S, Mak TW. Cairns RA, et al. Cold Spring Harb Symp Quant Biol. 2011;76:299-311. doi: 10.1101/sqb.2011.76.012856. Epub 2011 Dec 12. Cold Spring Harb Symp Quant Biol. 2011. PMID: 22156302 Review.
IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma.
Cairns RA, Iqbal J, Lemonnier F, Kucuk C, de Leval L, Jais JP, Parrens M, Martin A, Xerri L, Brousset P, Chan LC, Chan WC, Gaulard P, Mak TW. Cairns RA, et al. Blood. 2012 Feb 23;119(8):1901-3. doi: 10.1182/blood-2011-11-391748. Epub 2012 Jan 3. Blood. 2012. PMID: 22215888 Free PMC article.
Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters.
Lemonnier F, Couronné L, Parrens M, Jaïs JP, Travert M, Lamant L, Tournillac O, Rousset T, Fabiani B, Cairns RA, Mak T, Bastard C, Bernard OA, de Leval L, Gaulard P. Lemonnier F, et al. Among authors: cairns ra. Blood. 2012 Aug 16;120(7):1466-9. doi: 10.1182/blood-2012-02-408542. Epub 2012 Jul 3. Blood. 2012. PMID: 22760778 Free article.
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.
Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW. Sasaki M, et al. Among authors: cairns ra. Genes Dev. 2012 Sep 15;26(18):2038-49. doi: 10.1101/gad.198200.112. Epub 2012 Aug 27. Genes Dev. 2012. PMID: 22925884 Free PMC article.
Mutant IDH is sufficient to initiate enchondromatosis in mice.
Hirata M, Sasaki M, Cairns RA, Inoue S, Puviindran V, Li WY, Snow BE, Jones LD, Wei Q, Sato S, Tang YJ, Nadesan P, Rockel J, Whetstone H, Poon R, Weng A, Gross S, Straley K, Gliser C, Xu Y, Wunder J, Mak TW, Alman BA. Hirata M, et al. Among authors: cairns ra. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2829-34. doi: 10.1073/pnas.1424400112. Epub 2015 Feb 17. Proc Natl Acad Sci U S A. 2015. PMID: 25730874 Free PMC article.
Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.
Itsumi M, Inoue S, Elia AJ, Murakami K, Sasaki M, Lind EF, Brenner D, Harris IS, Chio II, Afzal S, Cairns RA, Cescon DW, Elford AR, Ye J, Lang PA, Li WY, Wakeham A, Duncan GS, Haight J, You-Ten A, Snow B, Yamamoto K, Ohashi PS, Mak TW. Itsumi M, et al. Among authors: cairns ra. Cell Death Differ. 2015 Nov;22(11):1837-45. doi: 10.1038/cdd.2015.38. Epub 2015 Apr 17. Cell Death Differ. 2015. PMID: 25882048 Free PMC article.
67 results