Balachandran R - Search Results

1

Total Synthesis and Biological Evaluation of Tubulysin Analogues.

Colombo R, Wang Z, Han J, Balachandran R, Daghestani HN, Camarco DP, Vogt A, Day BW, Mendel D, Wipf P. Colombo R, et al. Among authors: balachandran r. J Org Chem. 2016 Nov 4;81(21):10302-10320. doi: 10.1021/acs.joc.6b01314. Epub 2016 Aug 5. J Org Chem. 2016. PMID: 27447195

2

Synthesis and biological evaluation of structurally highly modified analogues of the antimitotic natural product curacin A.

Wipf P, Reeves JT, Balachandran R, Day BW. Wipf P, et al. Among authors: balachandran r. J Med Chem. 2002 Apr 25;45(9):1901-17. doi: 10.1021/jm0105171. J Med Chem. 2002. PMID: 11960501

3

Discodermolide/Dictyostatin hybrids: synthesis and biological evaluation.

Shin Y, Choy N, Turner TR, Balachandran R, Madiraju C, Day BW, Curran DP. Shin Y, et al. Among authors: balachandran r. Org Lett. 2002 Dec 12;4(25):4443-6. doi: 10.1021/ol026942l. Org Lett. 2002. PMID: 12465908

4

Synthesis and biological evaluation of purealin and analogues as cytoplasmic dynein heavy chain inhibitors.

Zhu G, Yang F, Balachandran R, Höök P, Vallee RB, Curran DP, Day BW. Zhu G, et al. Among authors: balachandran r. J Med Chem. 2006 Mar 23;49(6):2063-76. doi: 10.1021/jm051030l. J Med Chem. 2006. PMID: 16539395

5

Total synthesis and biological evaluation of C16 analogs of (-)-dictyostatin.

Jung WH, Harrison C, Shin Y, Fournier JH, Balachandran R, Raccor BS, Sikorski RP, Vogt A, Curran DP, Day BW. Jung WH, et al. Among authors: balachandran r. J Med Chem. 2007 Jun 28;50(13):2951-66. doi: 10.1021/jm061385k. Epub 2007 Jun 2. J Med Chem. 2007. PMID: 17542572

6

A simplified synthesis of novel dictyostatin analogues with in vitro activity against epothilone B-resistant cells and antiangiogenic activity in zebrafish embryos.

Vollmer LL, Jiménez M, Camarco DP, Zhu W, Daghestani HN, Balachandran R, Reese CE, Lazo JS, Hukriede NA, Curran DP, Day BW, Vogt A. Vollmer LL, et al. Among authors: balachandran r. Mol Cancer Ther. 2011 Jun;10(6):994-1006. doi: 10.1158/1535-7163.MCT-10-1048. Epub 2011 Apr 13. Mol Cancer Ther. 2011. PMID: 21490306 Free PMC article.

7

Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs.

Wan S, Wu F, Rech JC, Green ME, Balachandran R, Horne WS, Day BW, Floreancig PE. Wan S, et al. Among authors: balachandran r. J Am Chem Soc. 2011 Oct 19;133(41):16668-79. doi: 10.1021/ja207331m. Epub 2011 Sep 22. J Am Chem Soc. 2011. PMID: 21902245

8

Synthesis and biological evaluation of neopeltolide and analogs.

Cui Y, Balachandran R, Day BW, Floreancig PE. Cui Y, et al. Among authors: balachandran r. J Org Chem. 2012 Mar 2;77(5):2225-35. doi: 10.1021/jo2023685. Epub 2012 Feb 22. J Org Chem. 2012. PMID: 22329423 Free PMC article.

9

Synthesis and high content cell-based profiling of simplified analogues of the microtubule stabilizer (+)-discodermolide.

Minguez JM, Giuliano KA, Balachandran R, Madiraju C, Curran DP, Day BW. Minguez JM, et al. Among authors: balachandran r. Mol Cancer Ther. 2002 Dec;1(14):1305-13. Mol Cancer Ther. 2002. PMID: 12516963

10

Simplified discodermolide analogues: synthesis and biological evaluation of 4-epi-7-dehydroxy-14,16-didemethyl-(+)-discodermolides as microtubule-stabilizing agents.

Choy N, Shin Y, Nguyen PQ, Curran DP, Balachandran R, Madiraju C, Day BW. Choy N, et al. Among authors: balachandran r. J Med Chem. 2003 Jul 3;46(14):2846-64. doi: 10.1021/jm0204136. J Med Chem. 2003. PMID: 12825928

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