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MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment.
Leoncini PP, Bertaina A, Papaioannou D, Flotho C, Masetti R, Bresolin S, Menna G, Santoro N, Zecca M, Basso G, Nigita G, Veneziano D, Pagotto S, D'Ovidio K, Rota R, Dorrance A, Croce CM, Niemeyer C, Locatelli F, Garzon R. Leoncini PP, et al. Oncotarget. 2016 Aug 23;7(34):55395-55408. doi: 10.18632/oncotarget.10577. Oncotarget. 2016. PMID: 27447965 Free PMC article.
Serum miR-29a Is Upregulated in Acute Graft-versus-Host Disease and Activates Dendritic Cells through TLR Binding.
Ranganathan P, Ngankeu A, Zitzer NC, Leoncini P, Yu X, Casadei L, Challagundla K, Reichenbach DK, Garman S, Ruppert AS, Volinia S, Hofstetter J, Efebera YA, Devine SM, Blazar BR, Fabbri M, Garzon R. Ranganathan P, et al. J Immunol. 2017 Mar 15;198(6):2500-2512. doi: 10.4049/jimmunol.1601778. Epub 2017 Feb 3. J Immunol. 2017. PMID: 28159900 Free PMC article.
MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma.
Vella S, Pomella S, Leoncini PP, Colletti M, Conti B, Marquez VE, Strillacci A, Roma J, Gallego S, Milano GM, Capogrossi MC, Bertaina A, Ciarapica R, Rota R. Vella S, et al. Among authors: leoncini pp. Clin Epigenetics. 2015 Aug 6;7(1):82. doi: 10.1186/s13148-015-0107-z. eCollection 2015. Clin Epigenetics. 2015. PMID: 26251675 Free PMC article.
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS.
Ciarapica R, Carcarino E, Adesso L, De Salvo M, Bracaglia G, Leoncini PP, Dall'agnese A, Verginelli F, Milano GM, Boldrini R, Inserra A, Stifani S, Screpanti I, Marquez VE, Valente S, Mai A, Puri PL, Locatelli F, Palacios D, Rota R. Ciarapica R, et al. Among authors: leoncini pp. BMC Cancer. 2014 Feb 27;14:139. doi: 10.1186/1471-2407-14-139. BMC Cancer. 2014. PMID: 24575771 Free PMC article.
The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx).
Ciarapica R, De Salvo M, Carcarino E, Bracaglia G, Adesso L, Leoncini PP, Dall'Agnese A, Walters ZS, Verginelli F, De Sio L, Boldrini R, Inserra A, Bisogno G, Rosolen A, Alaggio R, Ferrari A, Collini P, Locatelli M, Stifani S, Screpanti I, Rutella S, Yu Q, Marquez VE, Shipley J, Valente S, Mai A, Miele L, Puri PL, Locatelli F, Palacios D, Rota R. Ciarapica R, et al. Among authors: leoncini pp. Oncogene. 2014 Aug 7;33(32):4173-84. doi: 10.1038/onc.2013.471. Epub 2013 Nov 11. Oncogene. 2014. PMID: 24213577
HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.
Strappazzon F, Di Rita A, Peschiaroli A, Leoncini PP, Locatelli F, Melino G, Cecconi F. Strappazzon F, et al. Among authors: leoncini pp. Cell Death Differ. 2020 Apr;27(4):1155-1168. doi: 10.1038/s41418-019-0404-8. Epub 2019 Aug 21. Cell Death Differ. 2020. PMID: 31434979 Free PMC article.
Comparison of the clinical usefulness of different urinary tests for the initial detection of bladder cancer: a systematic review.
Sciarra A, Di Lascio G, Del Giudice F, Leoncini PP, Salciccia S, Gentilucci A, Porreca A, Chung BI, Di Pierro G, Busetto GM, De Berardinis E, Maggi M. Sciarra A, et al. Among authors: leoncini pp. Curr Urol. 2021 Mar;15(1):22-32. doi: 10.1097/CU9.0000000000000012. Epub 2021 Mar 29. Curr Urol. 2021. PMID: 34084118 Free PMC article. Review.
33 results