Meggers E - Search Results

1

PIM kinases as therapeutic targets against advanced melanoma.

Shannan B, Watters A, Chen Q, Mollin S, Dörr M, Meggers E, Xu X, Gimotty PA, Perego M, Li L, Benci J, Krepler C, Brafford P, Zhang J, Wei Z, Zhang G, Liu Q, Yin X, Nathanson KL, Herlyn M, Vultur A. Shannan B, et al. Among authors: meggers e. Oncotarget. 2016 Aug 23;7(34):54897-54912. doi: 10.18632/oncotarget.10703. Oncotarget. 2016. PMID: 27448973 Free PMC article.

2

Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor.

Anand R, Maksimoska J, Pagano N, Wong EY, Gimotty PA, Diamond SL, Meggers E, Marmorstein R. Anand R, et al. Among authors: meggers e. J Med Chem. 2009 Mar 26;52(6):1602-11. doi: 10.1021/jm8005806. J Med Chem. 2009. PMID: 19226137 Free PMC article.

3

Rhenium complexes with visible-light-induced anticancer activity.

Kastl A, Dieckmann S, Wähler K, Völker T, Kastl L, Merkel AL, Vultur A, Shannan B, Harms K, Ocker M, Parak WJ, Herlyn M, Meggers E. Kastl A, et al. Among authors: meggers e. ChemMedChem. 2013 Jun;8(6):924-7. doi: 10.1002/cmdc.201300060. Epub 2013 Apr 8. ChemMedChem. 2013. PMID: 23568508 Free PMC article.

4

Metal complexes as structural templates for targeting proteins.

Dörr M, Meggers E. Dörr M, et al. Among authors: meggers e. Curr Opin Chem Biol. 2014 Apr;19:76-81. doi: 10.1016/j.cbpa.2014.01.005. Epub 2014 Feb 19. Curr Opin Chem Biol. 2014. PMID: 24561508 Review.

5

Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity.

Xie P, Williams DS, Atilla-Gokcumen GE, Milk L, Xiao M, Smalley KS, Herlyn M, Meggers E, Marmorstein R. Xie P, et al. Among authors: meggers e. ACS Chem Biol. 2008 May 16;3(5):305-16. doi: 10.1021/cb800039y. ACS Chem Biol. 2008. PMID: 18484710 Free PMC article.

6

GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation.

John JK, Paraiso KH, Rebecca VW, Cantini LP, Abel EV, Pagano N, Meggers E, Mathew R, Krepler C, Izumi V, Fang B, Koomen JM, Messina JL, Herlyn M, Smalley KS. John JK, et al. Among authors: meggers e. J Invest Dermatol. 2012 Dec;132(12):2818-27. doi: 10.1038/jid.2012.237. Epub 2012 Jul 19. J Invest Dermatol. 2012. PMID: 22810307 Free PMC article.

7

An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells.

Smalley KS, Contractor R, Haass NK, Kulp AN, Atilla-Gokcumen GE, Williams DS, Bregman H, Flaherty KT, Soengas MS, Meggers E, Herlyn M. Smalley KS, et al. Among authors: meggers e. Cancer Res. 2007 Jan 1;67(1):209-17. doi: 10.1158/0008-5472.CAN-06-1538. Cancer Res. 2007. PMID: 17210701

8

Octahedral rhodium(III) complexes as kinase inhibitors: Control of the relative stereochemistry with acyclic tridentate ligands.

Mollin S, Riedel R, Harms K, Meggers E. Mollin S, et al. Among authors: meggers e. J Inorg Biochem. 2015 Jul;148:11-21. doi: 10.1016/j.jinorgbio.2015.01.005. Epub 2015 Jan 22. J Inorg Biochem. 2015. PMID: 25660487

9

Organometallic Pyridylnaphthalimide Complexes as Protein Kinase Inhibitors.

Blanck S, Cruchter T, Vultur A, Riedel R, Harms K, Herlyn M, Meggers E. Blanck S, et al. Among authors: meggers e. Organometallics. 2011 Jul 18;30(17):4598-4606. doi: 10.1021/om200366r. Organometallics. 2011. PMID: 21918590 Free PMC article.

10

Similar biological activities of two isostructural ruthenium and osmium complexes.

Maksimoska J, Williams DS, Atilla-Gokcumen GE, Smalley KS, Carroll PJ, Webster RD, Filippakopoulos P, Knapp S, Herlyn M, Meggers E. Maksimoska J, et al. Among authors: meggers e. Chemistry. 2008;14(16):4816-22. doi: 10.1002/chem.200800294. Chemistry. 2008. PMID: 18425743 Free PMC article.

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