Choudhary M - Search Results

1

Rethinking Nuclear Receptors as Potential Therapeutic Targets for Retinal Diseases.

Choudhary M, Malek G. Choudhary M, et al. J Biomol Screen. 2016 Dec;21(10):1007-1018. doi: 10.1177/1087057116659856. Epub 2016 Jul 28. J Biomol Screen. 2016. PMID: 27455994 Free PMC article. Review.

2

Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways.

Choudhary M, Kazmin D, Hu P, Thomas RS, McDonnell DP, Malek G. Choudhary M, et al. J Pathol. 2015 Jan;235(1):101-12. doi: 10.1002/path.4433. Epub 2014 Oct 10. J Pathol. 2015. PMID: 25186463 Free PMC article.

3

A Brief Discussion on Lipid Activated Nuclear Receptors and their Potential Role in Regulating Microglia in Age-Related Macular Degeneration (AMD).

Choudhary M, Malek G. Choudhary M, et al. Adv Exp Med Biol. 2016;854:45-51. doi: 10.1007/978-3-319-17121-0_7. Adv Exp Med Biol. 2016. PMID: 26427392 Free PMC article. Review.

4

PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration.

Choudhary M, Ding JD, Qi X, Boulton ME, Yao PL, Peters JM, Malek G. Choudhary M, et al. Aging (Albany NY). 2016 Sep 8;8(9):1952-1978. doi: 10.18632/aging.101031. Aging (Albany NY). 2016. PMID: 27622388 Free PMC article.

5

Models of retinal diseases and their applicability in drug discovery.

Malek G, Busik J, Grant MB, Choudhary M. Malek G, et al. Among authors: choudhary m. Expert Opin Drug Discov. 2018 Apr;13(4):359-377. doi: 10.1080/17460441.2018.1430136. Epub 2018 Jan 30. Expert Opin Drug Discov. 2018. PMID: 29382242 Free PMC article. Review.

6

Suppression of aberrant choroidal neovascularization through activation of the aryl hydrocarbon receptor.

Choudhary M, Safe S, Malek G. Choudhary M, et al. Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1583-1595. doi: 10.1016/j.bbadis.2018.02.015. Epub 2018 Feb 23. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29481912 Free PMC article.

7

Impaired monocyte cholesterol clearance initiates age-related retinal degeneration and vision loss.

Ban N, Lee TJ, Sene A, Choudhary M, Lekwuwa M, Dong Z, Santeford A, Lin JB, Malek G, Ory DS, Apte RS. Ban N, et al. Among authors: choudhary m. JCI Insight. 2018 Sep 6;3(17):e120824. doi: 10.1172/jci.insight.120824. eCollection 2018 Sep 6. JCI Insight. 2018. PMID: 30185655 Free PMC article.

8

LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target.

Choudhary M, Ismail EN, Yao PL, Tayyari F, Radu RA, Nusinowitz S, Boulton ME, Apte RS, Ruberti JW, Handa JT, Tontonoz P, Malek G. Choudhary M, et al. JCI Insight. 2020 Jan 16;5(1):e131928. doi: 10.1172/jci.insight.131928. JCI Insight. 2020. PMID: 31829999 Free PMC article.

9

A Review of Pathogenic Drivers of Age-Related Macular Degeneration, Beyond Complement, with a Focus on Potential Endpoints for Testing Therapeutic Interventions in Preclinical Studies.

Choudhary M, Malek G. Choudhary M, et al. Adv Exp Med Biol. 2019;1185:9-13. doi: 10.1007/978-3-030-27378-1_2. Adv Exp Med Biol. 2019. PMID: 31884581 Free PMC article. Review.

10

The Aryl Hydrocarbon Receptor: A Mediator and Potential Therapeutic Target for Ocular and Non-Ocular Neurodegenerative Diseases.

Choudhary M, Malek G. Choudhary M, et al. Int J Mol Sci. 2020 Sep 16;21(18):6777. doi: 10.3390/ijms21186777. Int J Mol Sci. 2020. PMID: 32947781 Free PMC article. Review.

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