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659 results

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Efficacy of the nanoparticle-drug conjugate CRLX101 in combination with bevacizumab in metastatic renal cell carcinoma: results of an investigator-initiated phase I-IIa clinical trial.
Keefe SM, Hoffman-Censits J, Cohen RB, Mamtani R, Heitjan D, Eliasof S, Nixon A, Turnbull B, Garmey EG, Gunnarsson O, Waliki M, Ciconte J, Jayaraman L, Senderowicz A, Tellez AB, Hennessy M, Piscitelli A, Vaughn D, Smith A, Haas NB. Keefe SM, et al. Among authors: hennessy m. Ann Oncol. 2016 Aug;27(8):1579-85. doi: 10.1093/annonc/mdw188. Epub 2016 Jun 8. Ann Oncol. 2016. PMID: 27457310 Free PMC article. Clinical Trial.
Updated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after ≥1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical trial.
Kaufman HL, Russell JS, Hamid O, Bhatia S, Terheyden P, D'Angelo SP, Shih KC, Lebbé C, Milella M, Brownell I, Lewis KD, Lorch JH, von Heydebreck A, Hennessy M, Nghiem P. Kaufman HL, et al. Among authors: hennessy m. J Immunother Cancer. 2018 Jan 19;6(1):7. doi: 10.1186/s40425-017-0310-x. J Immunother Cancer. 2018. PMID: 29347993 Free PMC article. Clinical Trial.
Efficacy and Safety of First-line Avelumab Treatment in Patients With Stage IV Metastatic Merkel Cell Carcinoma: A Preplanned Interim Analysis of a Clinical Trial.
D'Angelo SP, Russell J, Lebbé C, Chmielowski B, Gambichler T, Grob JJ, Kiecker F, Rabinowits G, Terheyden P, Zwiener I, Bajars M, Hennessy M, Kaufman HL. D'Angelo SP, et al. Among authors: hennessy m. JAMA Oncol. 2018 Sep 1;4(9):e180077. doi: 10.1001/jamaoncol.2018.0077. Epub 2018 Sep 13. JAMA Oncol. 2018. PMID: 29566106 Free PMC article. Clinical Trial.
Early objective response to avelumab treatment is associated with improved overall survival in patients with metastatic Merkel cell carcinoma.
D'Angelo SP, Hunger M, Brohl AS, Nghiem P, Bhatia S, Hamid O, Mehnert JM, Terheyden P, Shih KC, Brownell I, Lebbé C, Lewis KD, Linette GP, Milella M, Schlichting M, Hennessy MH, Bharmal M. D'Angelo SP, et al. Among authors: hennessy mh. Cancer Immunol Immunother. 2019 Apr;68(4):609-618. doi: 10.1007/s00262-018-02295-4. Epub 2019 Feb 5. Cancer Immunol Immunother. 2019. PMID: 30721341 Free PMC article. Clinical Trial.
How to address the challenges of evaluating treatment benefits-risks in rare diseases? A convergent mixed methods approach applied within a Merkel cell carcinoma phase 2 clinical trial.
Bharmal M, Guillemin I, Marrel A, Arnould B, Lambert J, Hennessy M, Fofana F. Bharmal M, et al. Among authors: hennessy m. Orphanet J Rare Dis. 2018 Jun 18;13(1):95. doi: 10.1186/s13023-018-0835-1. Orphanet J Rare Dis. 2018. PMID: 29914528 Free PMC article. Clinical Trial.
Update on the psychometric properties and minimal important difference (MID) thresholds of the FACT-M questionnaire for use in treatment-naïve and previously treated patients with metastatic Merkel cell carcinoma.
Bharmal M, Nolte S, Henry-Szatkowski M, Hennessy M, Schlichting M. Bharmal M, et al. Among authors: hennessy m. Health Qual Life Outcomes. 2020 May 19;18(1):145. doi: 10.1186/s12955-020-01402-3. Health Qual Life Outcomes. 2020. PMID: 32430019 Free PMC article.
Evaluation of the potential for QTc prolongation with avelumab.
Vugmeyster Y, Güzel G, Hennessy M, Loos AH, Dai H. Vugmeyster Y, et al. Among authors: hennessy m. Cancer Chemother Pharmacol. 2019 Nov;84(5):1017-1026. doi: 10.1007/s00280-019-03925-z. Epub 2019 Sep 3. Cancer Chemother Pharmacol. 2019. PMID: 31478078 Free PMC article.
659 results