Aboussekhra A - Search Results

1

PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells.

Al-Howail HA, Hakami HA, Al-Otaibi B, Al-Mazrou A, Daghestani MH, Al-Jammaz I, Al-Khalaf HH, Aboussekhra A. Al-Howail HA, et al. Among authors: aboussekhra a. BMC Cancer. 2016 Jul 27;16:540. doi: 10.1186/s12885-016-2583-8. BMC Cancer. 2016. PMID: 27465411 Free PMC article.

2

Benign tumors from the human nervous system express high levels of survivin and are resistant to spontaneous and radiation-induced apoptosis.

Hassounah M, Lach B, Allam A, Al-Khalaf H, Siddiqui Y, Pangue-Cruz N, Al-Omeir A, Al-Ahdal MN, Aboussekhra A. Hassounah M, et al. Among authors: aboussekhra a. J Neurooncol. 2005 May;72(3):203-8. doi: 10.1007/s11060-004-2397-4. J Neurooncol. 2005. PMID: 15937641

3

The p16INK4a tumor suppressor controls p21WAF1 induction in response to ultraviolet light.

Al-Mohanna MA, Al-Khalaf HH, Al-Yousef N, Aboussekhra A. Al-Mohanna MA, et al. Among authors: aboussekhra a. Nucleic Acids Res. 2007;35(1):223-33. doi: 10.1093/nar/gkl1075. Epub 2006 Dec 7. Nucleic Acids Res. 2007. PMID: 17158160 Free PMC article.

4

The p53/p21 DNA damage-signaling pathway is defective in most meningioma cells.

Al-Khalaf HH, Lach B, Allam A, AlKhani A, Alrokayan SA, Aboussekhra A. Al-Khalaf HH, et al. Among authors: aboussekhra a. J Neurooncol. 2007 May;83(1):9-15. doi: 10.1007/s11060-006-9301-3. Epub 2007 Jan 24. J Neurooncol. 2007. PMID: 17245624

5

Expression of survivin and p16(INK4a)/Cdk6/pRB proteins and induction of apoptosis in response to radiation and cisplatin in meningioma cells.

Al-Khalaf HH, Lach B, Allam A, Hassounah M, Alkhani A, Elkum N, Alrokayan SA, Aboussekhra A. Al-Khalaf HH, et al. Among authors: aboussekhra a. Brain Res. 2008 Jan 10;1188:25-34. doi: 10.1016/j.brainres.2007.10.074. Epub 2007 Nov 4. Brain Res. 2008. PMID: 18048012

6

Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes.

Hawsawi NM, Ghebeh H, Hendrayani SF, Tulbah A, Al-Eid M, Al-Tweigeri T, Ajarim D, Alaiya A, Dermime S, Aboussekhra A. Hawsawi NM, et al. Among authors: aboussekhra a. Cancer Res. 2008 Apr 15;68(8):2717-25. doi: 10.1158/0008-5472.CAN-08-0192. Cancer Res. 2008. PMID: 18413739

7

Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule.

Ghebeh H, Lehe C, Barhoush E, Al-Romaih K, Tulbah A, Al-Alwan M, Hendrayani SF, Manogaran P, Alaiya A, Al-Tweigeri T, Aboussekhra A, Dermime S. Ghebeh H, et al. Among authors: aboussekhra a. Breast Cancer Res. 2010;12(4):R48. doi: 10.1186/bcr2605. Epub 2010 Jul 13. Breast Cancer Res. 2010. PMID: 20626886 Free PMC article.

8

PAC, a novel curcumin analogue, has anti-breast cancer properties with higher efficiency on ER-negative cells.

Al-Hujaily EM, Mohamed AG, Al-Sharif I, Youssef KM, Manogaran PS, Al-Otaibi B, Al-Haza'a A, Al-Jammaz I, Al-Hussein K, Aboussekhra A. Al-Hujaily EM, et al. Among authors: aboussekhra a. Breast Cancer Res Treat. 2011 Jul;128(1):97-107. doi: 10.1007/s10549-010-1089-3. Epub 2010 Aug 1. Breast Cancer Res Treat. 2011. PMID: 20680677

9

The atr protein kinase controls UV-dependent upregulation of p16INK4A through inhibition of Skp2-related polyubiquitination/degradation.

Al-Khalaf HH, Hendrayani SF, Aboussekhra A. Al-Khalaf HH, et al. Among authors: aboussekhra a. Mol Cancer Res. 2011 Mar;9(3):311-9. doi: 10.1158/1541-7786.MCR-10-0506. Epub 2011 Jan 26. Mol Cancer Res. 2011. PMID: 21270107 Free article.

10

p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.

Al-Khalaf HH, Colak D, Al-Saif M, Al-Bakheet A, Hendrayani SF, Al-Yousef N, Kaya N, Khabar KS, Aboussekhra A. Al-Khalaf HH, et al. Among authors: aboussekhra a. PLoS One. 2011;6(7):e21111. doi: 10.1371/journal.pone.0021111. Epub 2011 Jul 20. PLoS One. 2011. PMID: 21799732 Free PMC article.

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