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The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.
Crippa V, Cicardi ME, Ramesh N, Seguin SJ, Ganassi M, Bigi I, Diacci C, Zelotti E, Baratashvili M, Gregory JM, Dobson CM, Cereda C, Pandey UB, Poletti A, Carra S. Crippa V, et al. Among authors: cereda c. Hum Mol Genet. 2016 Sep 15;25(18):3908-3924. doi: 10.1093/hmg/ddw232. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466192 Free PMC article.
Proteostasis and ALS: protocol for a phase II, randomised, double-blind, placebo-controlled, multicentre clinical trial for colchicine in ALS (Co-ALS).
Mandrioli J, Crippa V, Cereda C, Bonetto V, Zucchi E, Gessani A, Ceroni M, Chio A, D'Amico R, Monsurrò MR, Riva N, Sabatelli M, Silani V, Simone IL, Sorarù G, Provenzani A, D'Agostino VG, Carra S, Poletti A. Mandrioli J, et al. Among authors: cereda c. BMJ Open. 2019 May 30;9(5):e028486. doi: 10.1136/bmjopen-2018-028486. BMJ Open. 2019. PMID: 31152038 Free PMC article.
HSC70 expression is reduced in lymphomonocytes of sporadic ALS patients and contributes to TDP-43 accumulation.
Arosio A, Cristofani R, Pansarasa O, Crippa V, Riva C, Sirtori R, Rodriguez-Menendez V, Riva N, Gerardi F, Lunetta C, Cereda C, Poletti A, Ferrarese C, Tremolizzo L, Sala G. Arosio A, et al. Among authors: cereda c. Amyotroph Lateral Scler Frontotemporal Degener. 2020 Feb;21(1-2):51-62. doi: 10.1080/21678421.2019.1672749. Epub 2019 Oct 30. Amyotroph Lateral Scler Frontotemporal Degener. 2020. PMID: 31663379
BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes.
Mediani L, Galli V, Carrà AD, Bigi I, Vinet J, Ganassi M, Antoniani F, Tiago T, Cimino M, Mateju D, Cereda C, Pansarasa O, Alberti S, Mandrioli J, Carra S. Mediani L, et al. Among authors: cereda c. Cell Stress Chaperones. 2020 Nov;25(6):1045-1058. doi: 10.1007/s12192-020-01141-w. Epub 2020 Jul 21. Cell Stress Chaperones. 2020. PMID: 32696179 Free PMC article.
403 results