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Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub.
Roncagalli R, Hauri S, Fiore F, Liang Y, Chen Z, Sansoni A, Kanduri K, Joly R, Malzac A, Lähdesmäki H, Lahesmaa R, Yamasaki S, Saito T, Malissen M, Aebersold R, Gstaiger M, Malissen B. Roncagalli R, et al. Among authors: fiore f. Nat Immunol. 2014 Apr;15(4):384-392. doi: 10.1038/ni.2843. Epub 2014 Mar 2. Nat Immunol. 2014. PMID: 24584089 Free PMC article.
The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells.
Roncagalli R, Cucchetti M, Jarmuzynski N, Grégoire C, Bergot E, Audebert S, Baudelet E, Menoita MG, Joachim A, Durand S, Suchanek M, Fiore F, Zhang L, Liang Y, Camoin L, Malissen M, Malissen B. Roncagalli R, et al. Among authors: fiore f. J Exp Med. 2016 Oct 17;213(11):2437-2457. doi: 10.1084/jem.20160579. Epub 2016 Sep 19. J Exp Med. 2016. PMID: 27647348 Free PMC article.
Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal.
Baranska A, Shawket A, Jouve M, Baratin M, Malosse C, Voluzan O, Vu Manh TP, Fiore F, Bajénoff M, Benaroch P, Dalod M, Malissen M, Henri S, Malissen B. Baranska A, et al. Among authors: fiore f. J Exp Med. 2018 Apr 2;215(4):1115-1133. doi: 10.1084/jem.20171608. Epub 2018 Mar 6. J Exp Med. 2018. PMID: 29511065 Free PMC article.
Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy.
Celis-Gutierrez J, Blattmann P, Zhai Y, Jarmuzynski N, Ruminski K, Grégoire C, Ounoughene Y, Fiore F, Aebersold R, Roncagalli R, Gstaiger M, Malissen B. Celis-Gutierrez J, et al. Among authors: fiore f. Cell Rep. 2019 Jun 11;27(11):3315-3330.e7. doi: 10.1016/j.celrep.2019.05.041. Cell Rep. 2019. PMID: 31189114 Free PMC article.
Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics.
Voisinne G, Kersse K, Chaoui K, Lu L, Chaix J, Zhang L, Goncalves Menoita M, Girard L, Ounoughene Y, Wang H, Burlet-Schiltz O, Luche H, Fiore F, Malissen M, Gonzalez de Peredo A, Liang Y, Roncagalli R, Malissen B. Voisinne G, et al. Among authors: fiore f. Nat Immunol. 2019 Nov;20(11):1530-1541. doi: 10.1038/s41590-019-0489-8. Epub 2019 Oct 7. Nat Immunol. 2019. PMID: 31591574 Free PMC article.
Selective STING stimulation in dendritic cells primes antitumor T cell responses.
Jneid B, Bochnakian A, Hoffmann C, Delisle F, Djacoto E, Sirven P, Denizeau J, Sedlik C, Gerber-Ferder Y, Fiore F, Akyol R, Brousse C, Kramer R, Walters I, Carlioz S, Salmon H, Malissen B, Dalod M, Piaggio E, Manel N. Jneid B, et al. Among authors: fiore f. Sci Immunol. 2023 Jan 13;8(79):eabn6612. doi: 10.1126/sciimmunol.abn6612. Epub 2023 Jan 13. Sci Immunol. 2023. PMID: 36638189
Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors.
Demerlé C, Gorvel L, Mello M, Pastor S, Degos C, Zarubica A, Angelis F, Fiore F, Nunes JA, Malissen B, Greillier L, Guittard G, Luche H, Barlesi F, Olive D. Demerlé C, et al. Among authors: fiore f. J Immunother Cancer. 2023 May;11(5):e006348. doi: 10.1136/jitc-2022-006348. J Immunother Cancer. 2023. PMID: 37230538 Free PMC article.
467 results