Castel S - Search Results

1

Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway.

Fagegaltier D, Falciatori I, Czech B, Castel S, Perrimon N, Simcox A, Hannon GJ. Fagegaltier D, et al. Among authors: castel s. Genes Dev. 2016 Jul 15;30(14):1623-35. doi: 10.1101/gad.284927.116. Genes Dev. 2016. PMID: 27474441 Free PMC article.

2

RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond.

Castel SE, Martienssen RA. Castel SE, et al. Nat Rev Genet. 2013 Feb;14(2):100-12. doi: 10.1038/nrg3355. Nat Rev Genet. 2013. PMID: 23329111 Free PMC article. Review.

3

The Conserved RNA Binding Cyclophilin, Rct1, Regulates Small RNA Biogenesis and Splicing Independent of Heterochromatin Assembly.

Chang AY, Castel SE, Ernst E, Kim HS, Martienssen RA. Chang AY, et al. Cell Rep. 2017 Jun 20;19(12):2477-2489. doi: 10.1016/j.celrep.2017.05.086. Cell Rep. 2017. PMID: 28636937 Free PMC article.

4

RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II.

Zaratiegui M, Castel SE, Irvine DV, Kloc A, Ren J, Li F, de Castro E, Marín L, Chang AY, Goto D, Cande WZ, Antequera F, Arcangioli B, Martienssen RA. Zaratiegui M, et al. Nature. 2011 Oct 16;479(7371):135-8. doi: 10.1038/nature10501. Nature. 2011. PMID: 22002604 Free PMC article.

5

Dicer in action at replication-transcription collisions.

Ren J, Castel SE, Martienssen RA. Ren J, et al. Mol Cell Oncol. 2015 Mar 9;2(3):e991224. doi: 10.4161/23723556.2014.991224. eCollection 2015 Jul-Sep. Mol Cell Oncol. 2015. PMID: 27308471 Free PMC article.

6

Cell type-specific genetic regulation of gene expression across human tissues.

Kim-Hellmuth S, Aguet F, Oliva M, Muñoz-Aguirre M, Kasela S, Wucher V, Castel SE, Hamel AR, Viñuela A, Roberts AL, Mangul S, Wen X, Wang G, Barbeira AN, Garrido-Martín D, Nadel BB, Zou Y, Bonazzola R, Quan J, Brown A, Martinez-Perez A, Soria JM; GTEx Consortium; Getz G, Dermitzakis ET, Small KS, Stephens M, Xi HS, Im HK, Guigó R, Segrè AV, Stranger BE, Ardlie KG, Lappalainen T. Kim-Hellmuth S, et al. Among authors: castel se. Science. 2020 Sep 11;369(6509):eaaz8528. doi: 10.1126/science.aaz8528. Science. 2020. PMID: 32913075 Free PMC article.

7

Dicer promotes transcription termination at sites of replication stress to maintain genome stability.

Castel SE, Ren J, Bhattacharjee S, Chang AY, Sánchez M, Valbuena A, Antequera F, Martienssen RA. Castel SE, et al. Cell. 2014 Oct 23;159(3):572-83. doi: 10.1016/j.cell.2014.09.031. Epub 2014 Oct 16. Cell. 2014. PMID: 25417108 Free PMC article.

8

Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk.

Castel SE, Cervera A, Mohammadi P, Aguet F, Reverter F, Wolman A, Guigo R, Iossifov I, Vasileva A, Lappalainen T. Castel SE, et al. Nat Genet. 2018 Sep;50(9):1327-1334. doi: 10.1038/s41588-018-0192-y. Epub 2018 Aug 20. Nat Genet. 2018. PMID: 30127527 Free PMC article.

9

Quantifying the regulatory effect size of cis-acting genetic variation using allelic fold change.

Mohammadi P, Castel SE, Brown AA, Lappalainen T. Mohammadi P, et al. Genome Res. 2017 Nov;27(11):1872-1884. doi: 10.1101/gr.216747.116. Epub 2017 Oct 11. Genome Res. 2017. PMID: 29021289 Free PMC article.

10

Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis.

Yang F, Wang J; GTEx Consortium; Pierce BL, Chen LS. Yang F, et al. Genome Res. 2017 Nov;27(11):1859-1871. doi: 10.1101/gr.216754.116. Epub 2017 Oct 11. Genome Res. 2017. PMID: 29021290 Free PMC article.

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