Trevino I - Search Results

1

Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding.

Huerta C, Jiang X, Trevino I, Bender CF, Ferguson DA, Probst B, Swinger KK, Stoll VS, Thomas PJ, Dulubova I, Visnick M, Wigley WC. Huerta C, et al. Among authors: trevino i. Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2537-2552. doi: 10.1016/j.bbagen.2016.07.026. Epub 2016 Jul 27. Biochim Biophys Acta. 2016. PMID: 27474998

2

Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405.

Probst BL, McCauley L, Trevino I, Wigley WC, Ferguson DA. Probst BL, et al. Among authors: trevino i. PLoS One. 2015 Aug 24;10(8):e0135257. doi: 10.1371/journal.pone.0135257. eCollection 2015. PLoS One. 2015. PMID: 26301506 Free PMC article.

3

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity.

Probst BL, Trevino I, McCauley L, Bumeister R, Dulubova I, Wigley WC, Ferguson DA. Probst BL, et al. Among authors: trevino i. PLoS One. 2015 Apr 21;10(4):e0122942. doi: 10.1371/journal.pone.0122942. eCollection 2015. PLoS One. 2015. PMID: 25897966 Free PMC article.

4

A novel series of cysteine-dependent, allosteric inverse agonists of the nuclear receptor RORγt.

Jiang X, Dulubova I, Reisman SA, Hotema M, Lee CI, Liu L, McCauley L, Trevino I, Ferguson DA, Eken Y, Wilson AK, Wigley WC, Visnick M. Jiang X, et al. Among authors: trevino i. Bioorg Med Chem Lett. 2020 Mar 15;30(6):126967. doi: 10.1016/j.bmcl.2020.126967. Epub 2020 Jan 15. Bioorg Med Chem Lett. 2020. PMID: 32005415

5

The synthetic triterpenoid, RTA 405, increases the glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells.

Ding Y, Stidham RD, Bumeister R, Trevino I, Winters A, Sprouse M, Ding M, Ferguson DA, Meyer CJ, Wigley WC, Ma R. Ding Y, et al. Among authors: trevino i. Kidney Int. 2013 May;83(5):845-54. doi: 10.1038/ki.2012.393. Epub 2012 Dec 12. Kidney Int. 2013. PMID: 23235569 Free PMC article.

6

Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents.

Zheng S, Santosh Laxmi YR, David E, Dinkova-Kostova AT, Shiavoni KH, Ren Y, Zheng Y, Trevino I, Bumeister R, Ojima I, Wigley WC, Bliska JB, Mierke DF, Honda T. Zheng S, et al. Among authors: trevino i. J Med Chem. 2012 May 24;55(10):4837-46. doi: 10.1021/jm3003922. Epub 2012 May 7. J Med Chem. 2012. PMID: 22533790

7

Parkin deficiency increases vulnerability to inflammation-related nigral degeneration.

Frank-Cannon TC, Tran T, Ruhn KA, Martinez TN, Hong J, Marvin M, Hartley M, Treviño I, O'Brien DE, Casey B, Goldberg MS, Tansey MG. Frank-Cannon TC, et al. Among authors: trevino i. J Neurosci. 2008 Oct 22;28(43):10825-34. doi: 10.1523/JNEUROSCI.3001-08.2008. J Neurosci. 2008. PMID: 18945890 Free PMC article.

8

The neuro-glial properties of adipose-derived adult stromal (ADAS) cells are not regulated by Notch 1 and are not derived from neural crest lineage.

Wrage PC, Tran T, To K, Keefer EW, Ruhn KA, Hong J, Hattangadi S, Treviño I, Tansey MG. Wrage PC, et al. Among authors: trevino i. PLoS One. 2008 Jan 16;3(1):e1453. doi: 10.1371/journal.pone.0001453. PLoS One. 2008. PMID: 18197263 Free PMC article.

9

AAV-dominant negative tumor necrosis factor (DN-TNF) gene transfer to the striatum does not rescue medium spiny neurons in the YAC128 mouse model of Huntington's disease.

Alto LT, Chen X, Ruhn KA, Treviño I, Tansey MG. Alto LT, et al. Among authors: trevino i. PLoS One. 2014 May 13;9(5):e96544. doi: 10.1371/journal.pone.0096544. eCollection 2014. PLoS One. 2014. PMID: 24824433 Free PMC article.

10

Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease.

Harms AS, Barnum CJ, Ruhn KA, Varghese S, Treviño I, Blesch A, Tansey MG. Harms AS, et al. Among authors: trevino i. Mol Ther. 2011 Jan;19(1):46-52. doi: 10.1038/mt.2010.217. Epub 2010 Oct 19. Mol Ther. 2011. PMID: 20959812 Free PMC article.

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