Kahle KT - Search Results

1

Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter.

Kahle KT, Flores B, Bharucha-Goebel D, Zhang J, Donkervoort S, Hegde M, Hussain G, Duran D, Liang B, Sun D, Bönnemann CG, Delpire E. Kahle KT, et al. Sci Signal. 2016 Aug 2;9(439):ra77. doi: 10.1126/scisignal.aae0546. Sci Signal. 2016. PMID: 27485015 Free PMC article.

2

Molecular mechanisms of ischemic cerebral edema: role of electroneutral ion transport.

Kahle KT, Simard JM, Staley KJ, Nahed BV, Jones PS, Sun D. Kahle KT, et al. Physiology (Bethesda). 2009 Aug;24:257-65. doi: 10.1152/physiol.00015.2009. Physiology (Bethesda). 2009. PMID: 19675357 Free article. Review.

3

Inhibition of Na(+)-K(+)-2Cl(-) cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells.

Algharabil J, Kintner DB, Wang Q, Begum G, Clark PA, Yang SS, Lin SH, Kahle KT, Kuo JS, Sun D. Algharabil J, et al. Among authors: kahle kt. Cell Physiol Biochem. 2012;30(1):33-48. doi: 10.1159/000339047. Epub 2012 Jun 8. Cell Physiol Biochem. 2012. PMID: 22759954 Free PMC article.

4

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2.

Kahle KT, Deeb TZ, Puskarjov M, Silayeva L, Liang B, Kaila K, Moss SJ. Kahle KT, et al. Trends Neurosci. 2013 Dec;36(12):726-737. doi: 10.1016/j.tins.2013.08.006. Epub 2013 Oct 15. Trends Neurosci. 2013. PMID: 24139641 Free PMC article. Review.

5

Persistent phosphorylation of NKCC1 and WNK1 in the epicenter of the spinal cord following contusion injury.

Lee HK, Ahmed MM, King KC, Miranpuri GS, Kahle KT, Resnick DK, Sun D. Lee HK, et al. Among authors: kahle kt. Spine J. 2014 May 1;14(5):777-81. doi: 10.1016/j.spinee.2013.06.100. Epub 2013 Nov 14. Spine J. 2014. PMID: 24239489

6

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.

de Los Heros P, Alessi DR, Gourlay R, Campbell DG, Deak M, Macartney TJ, Kahle KT, Zhang J. de Los Heros P, et al. Among authors: kahle kt. Biochem J. 2014 Mar 15;458(3):559-73. doi: 10.1042/BJ20131478. Biochem J. 2014. PMID: 24393035 Free PMC article.

7

Dysregulation of diverse ion transport pathways controlling cell volume homoestasis contribute to neuroglial cell injury following ischemic stroke.

Sun D, Kahle KT. Sun D, et al. Among authors: kahle kt. Transl Stroke Res. 2014 Feb;5(1):1-2. doi: 10.1007/s12975-014-0324-3. Epub 2014 Jan 27. Transl Stroke Res. 2014. PMID: 24464825 Free PMC article. No abstract available.

8

WNK1-OSR1 kinase-mediated phospho-activation of Na+-K+-2Cl- cotransporter facilitates glioma migration.

Zhu W, Begum G, Pointer K, Clark PA, Yang SS, Lin SH, Kahle KT, Kuo JS, Sun D. Zhu W, et al. Among authors: kahle kt. Mol Cancer. 2014 Feb 20;13:31. doi: 10.1186/1476-4598-13-31. Mol Cancer. 2014. PMID: 24555568 Free PMC article.

9

The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters.

Alessi DR, Zhang J, Khanna A, Hochdörfer T, Shang Y, Kahle KT. Alessi DR, et al. Among authors: kahle kt. Sci Signal. 2014 Jul 15;7(334):re3. doi: 10.1126/scisignal.2005365. Sci Signal. 2014. PMID: 25028718 Review.

10

Inhibition of WNK3 Kinase Signaling Reduces Brain Damage and Accelerates Neurological Recovery After Stroke.

Begum G, Yuan H, Kahle KT, Li L, Wang S, Shi Y, Shmukler BE, Yang SS, Lin SH, Alper SL, Sun D. Begum G, et al. Among authors: kahle kt. Stroke. 2015 Jul;46(7):1956-1965. doi: 10.1161/STROKEAHA.115.008939. Epub 2015 Jun 11. Stroke. 2015. PMID: 26069258 Free PMC article.

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