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Programed death-1/programed death-ligand 1 expression in lymph nodes of HIV infected patients: results of a pilot safety study in rhesus macaques using anti-programed death-ligand 1 (Avelumab).
Gill AL, Green SA, Abdullah S, Le Saout C, Pittaluga S, Chen H, Turnier R, Lifson J, Godin S, Qin J, Sneller MC, Cuillerot JM, Sabzevari H, Lane HC, Catalfamo M. Gill AL, et al. Among authors: lane hc. AIDS. 2016 Oct 23;30(16):2487-2493. doi: 10.1097/QAD.0000000000001217. AIDS. 2016. PMID: 27490642 Free PMC article.
The role of cytokines in the pathogenesis and treatment of HIV infection.
Catalfamo M, Le Saout C, Lane HC. Catalfamo M, et al. Among authors: lane hc. Cytokine Growth Factor Rev. 2012 Aug-Oct;23(4-5):207-14. doi: 10.1016/j.cytogfr.2012.05.007. Epub 2012 Jun 26. Cytokine Growth Factor Rev. 2012. PMID: 22738931 Free PMC article. Review.
Chronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis.
Le Saout C, Hasley RB, Imamichi H, Tcheung L, Hu Z, Luckey MA, Park JH, Durum SK, Smith M, Rupert AW, Sneller MC, Lane HC, Catalfamo M. Le Saout C, et al. Among authors: lane hc. PLoS Pathog. 2014 Mar 6;10(3):e1003976. doi: 10.1371/journal.ppat.1003976. eCollection 2014 Mar. PLoS Pathog. 2014. PMID: 24603698 Free PMC article.
An open-label phase 1 clinical trial of the anti-α4β7 monoclonal antibody vedolizumab in HIV-infected individuals.
Sneller MC, Clarridge KE, Seamon C, Shi V, Zorawski MD, Justement JS, Blazkova J, Huiting ED, Proschan MA, Mora JR, Shetzline M, Moir S, Lane HC, Chun TW, Fauci AS. Sneller MC, et al. Among authors: lane hc. Sci Transl Med. 2019 Sep 11;11(509):eaax3447. doi: 10.1126/scitranslmed.aax3447. Epub 2019 Sep 5. Sci Transl Med. 2019. PMID: 31488581 Clinical Trial.
IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion.
Le Saout C, Luckey MA, Villarino AV, Smith M, Hasley RB, Myers TG, Imamichi H, Park JH, O'Shea JJ, Lane HC, Catalfamo M. Le Saout C, et al. Among authors: lane hc. JCI Insight. 2017 Nov 16;2(22):e96228. doi: 10.1172/jci.insight.96228. eCollection 2017 Nov 16. JCI Insight. 2017. PMID: 29202461 Free PMC article.
Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques.
Waldmann TA, Lugli E, Roederer M, Perera LP, Smedley JV, Macallister RP, Goldman CK, Bryant BR, Decker JM, Fleisher TA, Lane HC, Sneller MC, Kurlander RJ, Kleiner DE, Pletcher JM, Figg WD, Yovandich JL, Creekmore SP. Waldmann TA, et al. Among authors: lane hc. Blood. 2011 May 5;117(18):4787-95. doi: 10.1182/blood-2010-10-311456. Epub 2011 Mar 8. Blood. 2011. PMID: 21385847 Free PMC article.
467 results