Shi LZ - Search Results

1

Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.

Shi LZ, Fu T, Guan B, Chen J, Blando JM, Allison JP, Xiong L, Subudhi SK, Gao J, Sharma P. Shi LZ, et al. Nat Commun. 2016 Aug 8;7:12335. doi: 10.1038/ncomms12335. Nat Commun. 2016. PMID: 27498556 Free PMC article.

2

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.

Gao J, Shi LZ, Zhao H, Chen J, Xiong L, He Q, Chen T, Roszik J, Bernatchez C, Woodman SE, Chen PL, Hwu P, Allison JP, Futreal A, Wargo JA, Sharma P. Gao J, et al. Among authors: shi lz. Cell. 2016 Oct 6;167(2):397-404.e9. doi: 10.1016/j.cell.2016.08.069. Epub 2016 Sep 22. Cell. 2016. PMID: 27667683 Free PMC article.

3

VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer.

Gao J, Ward JF, Pettaway CA, Shi LZ, Subudhi SK, Vence LM, Zhao H, Chen J, Chen H, Efstathiou E, Troncoso P, Allison JP, Logothetis CJ, Wistuba II, Sepulveda MA, Sun J, Wargo J, Blando J, Sharma P. Gao J, et al. Among authors: shi lz. Nat Med. 2017 May;23(5):551-555. doi: 10.1038/nm.4308. Epub 2017 Mar 27. Nat Med. 2017. PMID: 28346412 Free PMC article.

4

Blockade of CTLA-4 and PD-1 Enhances Adoptive T-cell Therapy Efficacy in an ICOS-Mediated Manner.

Shi LZ, Goswami S, Fu T, Guan B, Chen J, Xiong L, Zhang J, Ng Tang D, Zhang X, Vence L, Blando J, Allison JP, Collazo R, Gao J, Sharma P. Shi LZ, et al. Cancer Immunol Res. 2019 Nov;7(11):1803-1812. doi: 10.1158/2326-6066.CIR-18-0873. Epub 2019 Aug 29. Cancer Immunol Res. 2019. PMID: 31466995

5

Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling.

Shen H, Huang F, Zhang X, Ojo OA, Li Y, Trummell HQ, Anderson JC, Fiveash J, Bredel M, Yang ES, Willey CD, Chong Z, Bonner JA, Shi LZ. Shen H, et al. Among authors: shi lz. Nat Commun. 2022 Aug 25;13(1):5013. doi: 10.1038/s41467-022-32754-7. Nat Commun. 2022. PMID: 36008408 Free PMC article.

6

HIF1α-regulated glycolysis promotes activation-induced cell death and IFN-γ induction in hypoxic T cells.

Shen H, Ojo OA, Ding H, Mullen LJ, Xing C, Hossain MI, Yassin A, Shi VY, Lewis Z, Podgorska E, Andrabi SA, Antoniewicz MR, Bonner JA, Shi LZ. Shen H, et al. Among authors: shi lz. Nat Commun. 2024 Oct 30;15(1):9394. doi: 10.1038/s41467-024-53593-8. Nat Commun. 2024. PMID: 39477954 Free PMC article.

7

Bridging Radiotherapy to Immunotherapy: The IFN-JAK-STAT Axis.

Shi LZ, Bonner JA. Shi LZ, et al. Int J Mol Sci. 2021 Nov 14;22(22):12295. doi: 10.3390/ijms222212295. Int J Mol Sci. 2021. PMID: 34830176 Free PMC article.

8

Metabolic regulation of T_H17 cells.

Shen H, Shi LZ. Shen H, et al. Among authors: shi lz. Mol Immunol. 2019 May;109:81-87. doi: 10.1016/j.molimm.2019.03.005. Epub 2019 Mar 20. Mol Immunol. 2019. PMID: 30903829 Free PMC article. Review.

9

Predictive biomarkers for immune checkpoint blockade and opportunities for combination therapies.

Shen H, Yang ES, Conry M, Fiveash J, Contreras C, Bonner JA, Shi LZ. Shen H, et al. Among authors: shi lz. Genes Dis. 2019 Jul 3;6(3):232-246. doi: 10.1016/j.gendis.2019.06.006. eCollection 2019 Sep. Genes Dis. 2019. PMID: 32042863 Free PMC article. Review.

10

Editorial: Immune Cell Lineage Reprogramming in Cancer.

Leavenworth JW, Shi LZ, Wang X, Wei H. Leavenworth JW, et al. Among authors: shi lz. Front Immunol. 2022 Jan 19;12:838464. doi: 10.3389/fimmu.2021.838464. eCollection 2021. Front Immunol. 2022. PMID: 35126385 Free PMC article. No abstract available.

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