Mankin AS - Search Results

1

Binding of Macrolide Antibiotics Leads to Ribosomal Selection against Specific Substrates Based on Their Charge and Size.

Sothiselvam S, Neuner S, Rigger L, Klepacki D, Micura R, Vázquez-Laslop N, Mankin AS. Sothiselvam S, et al. Among authors: mankin as. Cell Rep. 2016 Aug 16;16(7):1789-99. doi: 10.1016/j.celrep.2016.07.018. Epub 2016 Aug 4. Cell Rep. 2016. PMID: 27498876 Free PMC article.

2

23S rRNA positions essential for tRNA binding in ribosomal functional sites.

Bocchetta M, Xiong L, Mankin AS. Bocchetta M, et al. Among authors: mankin as. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3525-30. doi: 10.1073/pnas.95.7.3525. Proc Natl Acad Sci U S A. 1998. PMID: 9520399 Free PMC article.

3

Effect of antibiotics on large ribosomal subunit assembly reveals possible function of 5 S rRNA.

Khaitovich P, Mankin AS. Khaitovich P, et al. Among authors: mankin as. J Mol Biol. 1999 Sep 3;291(5):1025-34. doi: 10.1006/jmbi.1999.3030. J Mol Biol. 1999. PMID: 10518940

4

[Ribosomal antibiotics].

Man'kin AS. Man'kin AS. Mol Biol (Mosk). 2001 Jul-Aug;35(4):597-609. Mol Biol (Mosk). 2001. PMID: 11524946 Review. Russian.

5

Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA.

Garza-Ramos G, Xiong L, Zhong P, Mankin A. Garza-Ramos G, et al. J Bacteriol. 2001 Dec;183(23):6898-907. doi: 10.1128/JB.183.23.6898-6907.2001. J Bacteriol. 2001. PMID: 11698379 Free PMC article.

6

The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.

Polacek N, Gomez MJ, Ito K, Xiong L, Nakamura Y, Mankin A. Polacek N, et al. Mol Cell. 2003 Jan;11(1):103-12. doi: 10.1016/s1097-2765(02)00825-0. Mol Cell. 2003. PMID: 12535525 Free article.

7

Macrolide antibiotics: binding site, mechanism of action, resistance.

Gaynor M, Mankin AS. Gaynor M, et al. Among authors: mankin as. Curr Top Med Chem. 2003;3(9):949-61. doi: 10.2174/1568026033452159. Curr Top Med Chem. 2003. PMID: 12678831 Review.

8

Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451.

Erlacher MD, Lang K, Shankaran N, Wotzel B, Hüttenhofer A, Micura R, Mankin AS, Polacek N. Erlacher MD, et al. Among authors: mankin as. Nucleic Acids Res. 2005 Mar 14;33(5):1618-27. doi: 10.1093/nar/gki308. Print 2005. Nucleic Acids Res. 2005. PMID: 15767286 Free PMC article.

9

SPARK: a new peptidyl transferase activity assay.

Mankin AS, Polacek N. Mankin AS, et al. Methods Mol Med. 2008;142:107-16. doi: 10.1007/978-1-59745-246-5_9. Methods Mol Med. 2008. PMID: 18437309

10

Molecular mechanism of drug-dependent ribosome stalling.

Vazquez-Laslop N, Thum C, Mankin AS. Vazquez-Laslop N, et al. Among authors: mankin as. Mol Cell. 2008 Apr 25;30(2):190-202. doi: 10.1016/j.molcel.2008.02.026. Mol Cell. 2008. PMID: 18439898 Free article.

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