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Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters.
Matthaei J, Tzvetkov MV, Gal V, Sachse-Seeboth C, Sehrt D, Hjelmborg JB, Hofmann U, Schwab M, Kerb R, Brockmöller J. Matthaei J, et al. Among authors: kerb r. Genome Med. 2016 Nov 8;8(1):119. doi: 10.1186/s13073-016-0372-2. Genome Med. 2016. PMID: 27825374 Free PMC article. Clinical Trial.
Heritability of metoprolol and torsemide pharmacokinetics.
Matthaei J, Brockmöller J, Tzvetkov MV, Sehrt D, Sachse-Seeboth C, Hjelmborg JB, Möller S, Halekoh U, Hofmann U, Schwab M, Kerb R. Matthaei J, et al. Among authors: kerb r. Clin Pharmacol Ther. 2015 Dec;98(6):611-21. doi: 10.1002/cpt.258. Epub 2015 Oct 19. Clin Pharmacol Ther. 2015. PMID: 26344676 Clinical Trial.
Inherited and Acquired Determinants of Hepatic CYP3A Activity in Humans.
Matthaei J, Bonat WH, Kerb R, Tzvetkov MV, Strube J, Brunke S, Sachse-Seeboth C, Sehrt D, Hofmann U, von Bornemann Hjelmborg J, Schwab M, Brockmöller J. Matthaei J, et al. Among authors: kerb r. Front Genet. 2020 Aug 21;11:944. doi: 10.3389/fgene.2020.00944. eCollection 2020. Front Genet. 2020. PMID: 32973880 Free PMC article.
Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment.
Fendt R, Hofmann U, Schneider ARP, Schaeffeler E, Burghaus R, Yilmaz A, Blank LM, Kerb R, Lippert J, Schlender JF, Schwab M, Kuepfer L. Fendt R, et al. Among authors: kerb r. CPT Pharmacometrics Syst Pharmacol. 2021 Jul;10(7):782-793. doi: 10.1002/psp4.12646. Epub 2021 Jun 26. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34053199 Free PMC article. Clinical Trial.
66 results