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Page 1
Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis.
Koliwer-Brandl H, Syson K, van de Weerd R, Chandra G, Appelmelk B, Alber M, Ioerger TR, Jacobs WR Jr, Geurtsen J, Bornemann S, Kalscheuer R. Koliwer-Brandl H, et al. Among authors: appelmelk b. PLoS Pathog. 2016 Aug 11;12(8):e1005768. doi: 10.1371/journal.ppat.1005768. eCollection 2016 Aug. PLoS Pathog. 2016. PMID: 27513637 Free PMC article.
A murine monoclonal antibody to glycogen: characterization of epitope-fine specificity by saturation transfer difference (STD) NMR spectroscopy and its use in mycobacterial capsular α-glucan research.
van de Weerd R, Berbís MA, Sparrius M, Maaskant JJ, Boot M, Paauw NJ, de Vries N, Boon L, Baba O, Cañada FJ, Geurtsen J, Jiménez-Barbero J, Appelmelk BJ. van de Weerd R, et al. Among authors: appelmelk bj. Chembiochem. 2015 Apr 13;16(6):977-89. doi: 10.1002/cbic.201402713. Epub 2015 Mar 12. Chembiochem. 2015. PMID: 25766777
Inorganic Phosphate Limitation Modulates Capsular Polysaccharide Composition in Mycobacteria.
van de Weerd R, Boot M, Maaskant J, Sparrius M, Verboom T, van Leeuwen LM, Burggraaf MJ, Paauw NJ, Dainese E, Manganelli R, Bitter W, Appelmelk BJ, Geurtsen J. van de Weerd R, et al. Among authors: appelmelk bj. J Biol Chem. 2016 May 27;291(22):11787-99. doi: 10.1074/jbc.M116.722454. Epub 2016 Apr 4. J Biol Chem. 2016. PMID: 27044743 Free PMC article.
Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo.
Romano M, van de Weerd R, Brouwer FC, Roviello GN, Lacroix R, Sparrius M, van den Brink-van Stempvoort G, Maaskant JJ, van der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R. Romano M, et al. Among authors: appelmelk bj. Structure. 2014 May 6;22(5):719-30. doi: 10.1016/j.str.2014.01.014. Epub 2014 Apr 3. Structure. 2014. PMID: 24704253 Free article.
Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity.
Stoop EJ, Mishra AK, Driessen NN, van Stempvoort G, Bouchier P, Verboom T, van Leeuwen LM, Sparrius M, Raadsen SA, van Zon M, van der Wel NN, Besra GS, Geurtsen J, Bitter W, Appelmelk BJ, van der Sar AM. Stoop EJ, et al. Among authors: appelmelk bj. Cell Microbiol. 2013 Dec;15(12):2093-108. doi: 10.1111/cmi.12175. Epub 2013 Aug 22. Cell Microbiol. 2013. PMID: 23902464 Free PMC article.
Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation.
Geurtsen J, Chedammi S, Mesters J, Cot M, Driessen NN, Sambou T, Kakutani R, Ummels R, Maaskant J, Takata H, Baba O, Terashima T, Bovin N, Vandenbroucke-Grauls CM, Nigou J, Puzo G, Lemassu A, Daffé M, Appelmelk BJ. Geurtsen J, et al. J Immunol. 2009 Oct 15;183(8):5221-31. doi: 10.4049/jimmunol.0900768. Epub 2009 Sep 25. J Immunol. 2009. PMID: 19783687
Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses.
Afonso-Barroso A, Clark SO, Williams A, Rosa GT, Nóbrega C, Silva-Gomes S, Vale-Costa S, Ummels R, Stoker N, Movahedzadeh F, van der Ley P, Sloots A, Cot M, Appelmelk BJ, Puzo G, Nigou J, Geurtsen J, Appelberg R. Afonso-Barroso A, et al. Among authors: appelmelk bj. Cell Microbiol. 2013 Apr;15(4):660-74. doi: 10.1111/cmi.12065. Epub 2012 Nov 21. Cell Microbiol. 2013. PMID: 23121245
125 results