Vucic D - Search Results

1

Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death.

de Almagro MC, Goncharov T, Izrael-Tomasevic A, Duttler S, Kist M, Varfolomeev E, Wu X, Lee WP, Murray J, Webster JD, Yu K, Kirkpatrick DS, Newton K, Vucic D. de Almagro MC, et al. Among authors: vucic d. Cell Death Differ. 2017 Jan;24(1):26-37. doi: 10.1038/cdd.2016.78. Epub 2016 Aug 12. Cell Death Differ. 2017. PMID: 27518435 Free PMC article.

2

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.

Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, Roose-Girma M, Erickson S, Dixit VM. Mariathasan S, et al. Among authors: vucic d. Nature. 2004 Jul 8;430(6996):213-8. doi: 10.1038/nature02664. Epub 2004 Jun 9. Nature. 2004. PMID: 15190255

3

Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand.

Varfolomeev E, Maecker H, Sharp D, Lawrence D, Renz M, Vucic D, Ashkenazi A. Varfolomeev E, et al. Among authors: vucic d. J Biol Chem. 2005 Dec 9;280(49):40599-608. doi: 10.1074/jbc.M509560200. Epub 2005 Oct 15. J Biol Chem. 2005. PMID: 16227629 Free article.

4

The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2.

Varfolomeev E, Wayson SM, Dixit VM, Fairbrother WJ, Vucic D. Varfolomeev E, et al. Among authors: vucic d. J Biol Chem. 2006 Sep 29;281(39):29022-9. doi: 10.1074/jbc.M605116200. Epub 2006 Aug 4. J Biol Chem. 2006. PMID: 16891304 Free article.

5

Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.

Zobel K, Wang L, Varfolomeev E, Franklin MC, Elliott LO, Wallweber HJ, Okawa DC, Flygare JA, Vucic D, Fairbrother WJ, Deshayes K. Zobel K, et al. Among authors: vucic d. ACS Chem Biol. 2006 Sep 19;1(8):525-33. doi: 10.1021/cb600276q. ACS Chem Biol. 2006. PMID: 17168540

6

Ubiquitin ligases in cancer: ushers for degradation.

Newton K, Vucic D. Newton K, et al. Among authors: vucic d. Cancer Invest. 2007 Sep;25(6):502-13. doi: 10.1080/07357900701508041. Cancer Invest. 2007. PMID: 17882664 Review.

7

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.

Varfolomeev E, Blankenship JW, Wayson SM, Fedorova AV, Kayagaki N, Garg P, Zobel K, Dynek JN, Elliott LO, Wallweber HJ, Flygare JA, Fairbrother WJ, Deshayes K, Dixit VM, Vucic D. Varfolomeev E, et al. Among authors: vucic d. Cell. 2007 Nov 16;131(4):669-81. doi: 10.1016/j.cell.2007.10.030. Cell. 2007. PMID: 18022362 Free article.

8

(Un)expected roles of c-IAPs in apoptotic and NFkappaB signaling pathways.

Varfolomeev E, Vucic D. Varfolomeev E, et al. Among authors: vucic d. Cell Cycle. 2008 Jun 1;7(11):1511-21. doi: 10.4161/cc.7.11.5959. Epub 2008 Mar 16. Cell Cycle. 2008. PMID: 18469528 Review.

9

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation.

Varfolomeev E, Goncharov T, Fedorova AV, Dynek JN, Zobel K, Deshayes K, Fairbrother WJ, Vucic D. Varfolomeev E, et al. Among authors: vucic d. J Biol Chem. 2008 Sep 5;283(36):24295-9. doi: 10.1074/jbc.C800128200. Epub 2008 Jul 11. J Biol Chem. 2008. PMID: 18621737 Free PMC article.

10

Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1).

Blankenship JW, Varfolomeev E, Goncharov T, Fedorova AV, Kirkpatrick DS, Izrael-Tomasevic A, Phu L, Arnott D, Aghajan M, Zobel K, Bazan JF, Fairbrother WJ, Deshayes K, Vucic D. Blankenship JW, et al. Among authors: vucic d. Biochem J. 2009 Jan 1;417(1):149-60. doi: 10.1042/BJ20081885. Biochem J. 2009. PMID: 18939944

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