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Piperazic acid derivatives inhibit Gli1 in Hedgehog signaling pathway.
Bioorg Med Chem Lett. 2016 Sep 15;26(18):4423-4426. doi: 10.1016/j.bmcl.2016.08.008. Epub 2016 Aug 4.
Bioorg Med Chem Lett. 2016.
PMID: 27528433
Discovery of Hedgehog Antagonists for Cancer Therapy.
Khatra H, Bose C, Sinha S.
Khatra H, et al.
Curr Med Chem. 2017;24(19):2033-2058. doi: 10.2174/0929867324666170316115500.
Curr Med Chem. 2017.
PMID: 28302010
Review.
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Hedgehog Antagonist Pyrimidine-Indole Hybrid Molecule Inhibits Ciliogenesis through Microtubule Destabilisation.
Khatra H, Khan PP, Pattanayak S, Bhadra J, Rather B, Chakrabarti S, Saha T, Sinha S.
Khatra H, et al.
Chembiochem. 2018 Apr 4;19(7):723-735. doi: 10.1002/cbic.201700631. Epub 2018 Mar 2.
Chembiochem. 2018.
PMID: 29363254
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