Chen YL - Search Results

1

Design and synthesis of benzylpiperidine inhibitors targeting the menin-MLL1 interface.

Ren J, Xu W, Tang L, Su M, Chen D, Chen YL, Zang Y, Li J, Shen J, Zhou Y, Xiong B. Ren J, et al. Among authors: chen yl, chen d. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4472-4476. doi: 10.1016/j.bmcl.2016.07.074. Epub 2016 Aug 2. Bioorg Med Chem Lett. 2016. PMID: 27528435

2

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus.

Chen YL, Tang J, Kesler MJ, Sham YY, Vince R, Geraghty RJ, Wang Z. Chen YL, et al. Bioorg Med Chem. 2012 Jan 1;20(1):467-79. doi: 10.1016/j.bmc.2011.10.058. Epub 2011 Oct 24. Bioorg Med Chem. 2012. PMID: 22100256

3

CCLab--a multi-objective genetic algorithm based combinatorial library design software and an application for histone deacetylase inhibitor design.

Fang G, Xue M, Su M, Hu D, Li Y, Xiong B, Ma L, Meng T, Chen Y, Li J, Li J, Shen J. Fang G, et al. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4540-5. doi: 10.1016/j.bmcl.2012.05.123. Epub 2012 Jun 7. Bioorg Med Chem Lett. 2012. PMID: 22738629

4

C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus.

Chen YL, Zacharias J, Vince R, Geraghty RJ, Wang Z. Chen YL, et al. Bioorg Med Chem. 2012 Aug 1;20(15):4790-800. doi: 10.1016/j.bmc.2012.05.066. Epub 2012 Jun 7. Bioorg Med Chem. 2012. PMID: 22748708

5

Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations.

Yu Z, Ma YC, Ai J, Chen DQ, Zhao DM, Wang X, Chen YL, Geng MY, Xiong B, Cheng MS, Shen JK. Yu Z, et al. Among authors: chen yl, chen dq. Acta Pharmacol Sin. 2013 Nov;34(11):1475-83. doi: 10.1038/aps.2013.85. Epub 2013 Sep 23. Acta Pharmacol Sin. 2013. PMID: 24056705 Free PMC article.

6

Synthesis and bioassay of β-(1,4)-D-mannans as potential agents against Alzheimer's disease.

Jiang RW, Du XG, Zhang X, Wang X, Hu DY, Meng T, Chen YL, Geng MY, Shen JK. Jiang RW, et al. Among authors: chen yl. Acta Pharmacol Sin. 2013 Dec;34(12):1585-91. doi: 10.1038/aps.2013.104. Epub 2013 Nov 18. Acta Pharmacol Sin. 2013. PMID: 24241344 Free PMC article.

7

Direct glycosylation of bioactive small molecules with glycosyl iodide and strained olefin as acid scavenger.

Gu X, Chen L, Wang X, Liu X, You Q, Xi W, Gao L, Chen G, Chen YL, Xiong B, Shen J. Gu X, et al. Among authors: chen l, chen yl, chen g. J Org Chem. 2014 Feb 7;79(3):1100-10. doi: 10.1021/jo402551x. J Org Chem. 2014. PMID: 24410364

8

Neoglycopeptide synthesis by suzuki-miyaura couplings between glycosyl aryl boronic acids and iodopeptides.

Chen G, Gu X, Chen L, Wang X, Chen YL, Shen J, Zeng W. Chen G, et al. Among authors: chen l, chen yl. Protein Pept Lett. 2014;21(10):1004-10. doi: 10.2174/0929866521666140626103204. Protein Pept Lett. 2014. PMID: 24975669

9

1,2-Tans-1-dihydroxyboryl benzyl S-glycoside as glycosyl donor.

Liu X, Zhang B, Gu X, Chen G, Chen L, Wang X, Xiong B, You QD, Chen YL, Shen J. Liu X, et al. Among authors: chen l, chen yl, chen g. Carbohydr Res. 2014 Oct 29;398:45-9. doi: 10.1016/j.carres.2014.05.010. Epub 2014 May 22. Carbohydr Res. 2014. PMID: 25240181

10

Strained olefin enables triflic anhydride mediated direct dehydrative glycosylation.

Chen G, Yin Q, Yin J, Gu X, Liu X, You Q, Chen YL, Xiong B, Shen J. Chen G, et al. Among authors: chen yl. Org Biomol Chem. 2014 Dec 28;12(48):9781-5. doi: 10.1039/c4ob01807a. Org Biomol Chem. 2014. PMID: 25370689

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