Mandrup S - Search Results

1

Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells.

Schmidt SF, Madsen JG, Frafjord KØ, Poulsen Ll, Salö S, Boergesen M, Loft A, Larsen BD, Madsen MS, Holst JJ, Maechler P, Dalgaard LT, Mandrup S. Schmidt SF, et al. Among authors: mandrup s. Cell Rep. 2016 Aug 30;16(9):2359-72. doi: 10.1016/j.celrep.2016.07.063. Epub 2016 Aug 18. Cell Rep. 2016. PMID: 27545881 Free article.

2

Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells.

Ravnskjaer K, Boergesen M, Rubi B, Larsen JK, Nielsen T, Fridriksson J, Maechler P, Mandrup S. Ravnskjaer K, et al. Among authors: mandrup s. Endocrinology. 2005 Aug;146(8):3266-76. doi: 10.1210/en.2004-1430. Epub 2005 May 5. Endocrinology. 2005. PMID: 15878969

3

Glucose-induced lipogenesis in pancreatic beta-cells is dependent on SREBP-1.

Sandberg MB, Fridriksson J, Madsen L, Rishi V, Vinson C, Holmsen H, Berge RK, Mandrup S. Sandberg MB, et al. Among authors: mandrup s. Mol Cell Endocrinol. 2005 Aug 30;240(1-2):94-106. doi: 10.1016/j.mce.2005.05.005. Mol Cell Endocrinol. 2005. PMID: 16002205

4

Glucose-induced repression of PPARalpha gene expression in pancreatic beta-cells involves PP2A activation and AMPK inactivation.

Ravnskjaer K, Boergesen M, Dalgaard LT, Mandrup S. Ravnskjaer K, et al. Among authors: mandrup s. J Mol Endocrinol. 2006 Apr;36(2):289-99. doi: 10.1677/jme.1.01965. J Mol Endocrinol. 2006. PMID: 16595700

5

Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.

Carobbio S, Frigerio F, Rubi B, Vetterli L, Bloksgaard M, Gjinovci A, Pournourmohammadi S, Herrera PL, Reith W, Mandrup S, Maechler P. Carobbio S, et al. Among authors: mandrup s. J Biol Chem. 2009 Jan 9;284(2):921-9. doi: 10.1074/jbc.M806295200. Epub 2008 Nov 17. J Biol Chem. 2009. PMID: 19015267 Free article.

6

Peroxisome proliferator-activated receptor-alpha is a functional target of p63 in adult human keratinocytes.

Pozzi S, Boergesen M, Sinha S, Mandrup S, Mantovani R. Pozzi S, et al. Among authors: mandrup s. J Invest Dermatol. 2009 Oct;129(10):2376-85. doi: 10.1038/jid.2009.92. Epub 2009 May 21. J Invest Dermatol. 2009. PMID: 19458633 Free article.

7

Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism.

Frigerio F, Brun T, Bartley C, Usardi A, Bosco D, Ravnskjaer K, Mandrup S, Maechler P. Frigerio F, et al. Among authors: mandrup s. Diabetologia. 2010 Feb;53(2):331-40. doi: 10.1007/s00125-009-1590-6. Epub 2009 Nov 12. Diabetologia. 2010. PMID: 19908022

8

PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction.

Ravnskjaer K, Frigerio F, Boergesen M, Nielsen T, Maechler P, Mandrup S. Ravnskjaer K, et al. Among authors: mandrup s. J Lipid Res. 2010 Jun;51(6):1370-9. doi: 10.1194/jlr.M001123. Epub 2009 Nov 30. J Lipid Res. 2010. PMID: 19965574 Free PMC article.

9

MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis.

Grøntved L, Madsen MS, Boergesen M, Roeder RG, Mandrup S. Grøntved L, et al. Among authors: mandrup s. Mol Cell Biol. 2010 May;30(9):2155-69. doi: 10.1128/MCB.01238-09. Epub 2010 Mar 1. Mol Cell Biol. 2010. PMID: 20194623 Free PMC article.

10

A novel intronic peroxisome proliferator-activated receptor gamma enhancer in the uncoupling protein (UCP) 3 gene as a regulator of both UCP2 and -3 expression in adipocytes.

Bugge A, Siersbaek M, Madsen MS, Göndör A, Rougier C, Mandrup S. Bugge A, et al. Among authors: mandrup s. J Biol Chem. 2010 Jun 4;285(23):17310-7. doi: 10.1074/jbc.M110.120584. Epub 2010 Apr 1. J Biol Chem. 2010. PMID: 20360005 Free PMC article.

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