Kuhn ML - Search Results

1

Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis.

Kuhn ML, Alexander E, Minasov G, Page HJ, Warwrzak Z, Shuvalova L, Flores KJ, Wilson DJ, Shi C, Aldrich CC, Anderson WF. Kuhn ML, et al. ACS Infect Dis. 2016 Aug 12;2(8):579-591. doi: 10.1021/acsinfecdis.6b00082. Epub 2016 Jul 1. ACS Infect Dis. 2016. PMID: 27547819 Free PMC article.

2

Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.

Makowska-Grzyska M, Kim Y, Wu R, Wilton R, Gollapalli DR, Wang XK, Zhang R, Jedrzejczak R, Mack JC, Maltseva N, Mulligan R, Binkowski TA, Gornicki P, Kuhn ML, Anderson WF, Hedstrom L, Joachimiak A. Makowska-Grzyska M, et al. Among authors: kuhn ml. Biochemistry. 2012 Aug 7;51(31):6148-63. doi: 10.1021/bi300511w. Epub 2012 Jul 25. Biochemistry. 2012. PMID: 22788966 Free PMC article.

3

Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificity.

Kuhn ML, Majorek KA, Minor W, Anderson WF. Kuhn ML, et al. Protein Sci. 2013 Feb;22(2):222-30. doi: 10.1002/pro.2199. Epub 2012 Dec 17. Protein Sci. 2013. PMID: 23184347 Free PMC article.

4

Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis.

Filippova EV, Weston LA, Kuhn ML, Geissler B, Gehring AM, Armoush N, Adkins CT, Minasov G, Dubrovska I, Shuvalova L, Winsor JR, Lavis LD, Satchell KJ, Becker DP, Anderson WF, Johnson RJ. Filippova EV, et al. Among authors: kuhn ml. J Biol Chem. 2013 Apr 12;288(15):10522-35. doi: 10.1074/jbc.M112.446625. Epub 2013 Feb 19. J Biol Chem. 2013. PMID: 23430251 Free PMC article.

5

Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.

Majorek KA, Kuhn ML, Chruszcz M, Anderson WF, Minor W. Majorek KA, et al. Among authors: kuhn ml. J Biol Chem. 2013 Oct 18;288(42):30223-30235. doi: 10.1074/jbc.M113.501353. Epub 2013 Sep 3. J Biol Chem. 2013. PMID: 24003232 Free PMC article.

6

Targeting DXP synthase in human pathogens: enzyme inhibition and antimicrobial activity of butylacetylphosphonate.

Smith JM, Warrington NV, Vierling RJ, Kuhn ML, Anderson WF, Koppisch AT, Freel Meyers CL. Smith JM, et al. Among authors: kuhn ml. J Antibiot (Tokyo). 2014 Jan;67(1):77-83. doi: 10.1038/ja.2013.105. Epub 2013 Oct 30. J Antibiot (Tokyo). 2014. PMID: 24169798 Free PMC article.

7

Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP.

Kuhn ML, Prachi P, Minasov G, Shuvalova L, Ruan J, Dubrovska I, Winsor J, Giraldi M, Biagini M, Liberatori S, Savino S, Bagnoli F, Anderson WF, Grandi G. Kuhn ML, et al. FASEB J. 2014 Apr;28(4):1780-93. doi: 10.1096/fj.13-241737. Epub 2014 Jan 13. FASEB J. 2014. PMID: 24421400 Free PMC article.

8

Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.

Kuhn ML, Zemaitaitis B, Hu LI, Sahu A, Sorensen D, Minasov G, Lima BP, Scholle M, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ. Kuhn ML, et al. PLoS One. 2014 Apr 22;9(4):e94816. doi: 10.1371/journal.pone.0094816. eCollection 2014. PLoS One. 2014. PMID: 24756028 Free PMC article.

9

Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments.

Majorek KA, Kuhn ML, Chruszcz M, Anderson WF, Minor W. Majorek KA, et al. Among authors: kuhn ml. Protein Sci. 2014 Oct;23(10):1359-68. doi: 10.1002/pro.2520. Epub 2014 Jul 30. Protein Sci. 2014. PMID: 25044180 Free PMC article.

10

Potential for reduction of streptogramin A resistance revealed by structural analysis of acetyltransferase VatA.

Stogios PJ, Kuhn ML, Evdokimova E, Courvalin P, Anderson WF, Savchenko A. Stogios PJ, et al. Among authors: kuhn ml. Antimicrob Agents Chemother. 2014 Dec;58(12):7083-92. doi: 10.1128/AAC.03743-14. Epub 2014 Sep 15. Antimicrob Agents Chemother. 2014. PMID: 25223995 Free PMC article.

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