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Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides.
Russell S, Rahmani R, Jones AJ, Newson HL, Neilde K, Cotillo I, Rahmani Khajouei M, Ferrins L, Qureishi S, Nguyen N, Martinez-Martinez MS, Weaver DF, Kaiser M, Riley J, Thomas J, De Rycker M, Read KD, Flematti GR, Ryan E, Tanghe S, Rodriguez A, Charman SA, Kessler A, Avery VM, Baell JB, Piggott MJ. Russell S, et al. Among authors: weaver df. J Med Chem. 2016 Nov 10;59(21):9686-9720. doi: 10.1021/acs.jmedchem.6b00442. Epub 2016 Sep 19. J Med Chem. 2016. PMID: 27548560 Free article.
Functionalized amido ketones: new anticonvulsant agents.
Béguin C, Andurkar SV, Jin AY, Stables JP, Weaver DF, Kohn H. Béguin C, et al. Among authors: weaver df. Bioorg Med Chem. 2003 Sep 15;11(19):4275-85. doi: 10.1016/s0968-0896(03)00434-6. Bioorg Med Chem. 2003. PMID: 12951158
Computer-aided drug design to generate a unique antibiotic family.
Barden CJ, Wu F, Fernandez-Murray JP, Lu E, Sun S, Taylor MM, Rushton AL, Williams J, Tavasoli M, Meek A, Reddy AS, Doyle LM, Sagamanova I, Sivamuthuraman K, Boudreau RTM, Byers DM, Weaver DF, McMaster CR. Barden CJ, et al. Among authors: weaver df. Nat Commun. 2024 Sep 27;15(1):8317. doi: 10.1038/s41467-024-52797-2. Nat Commun. 2024. PMID: 39333560 Free PMC article.
β-Amyloid Is a Kinocidin Cytokine.
Weaver DF. Weaver DF. ACS Chem Neurosci. 2024 May 15;15(10):1948-1950. doi: 10.1021/acschemneuro.4c00236. Epub 2024 Apr 29. ACS Chem Neurosci. 2024. PMID: 38684014
Chemists Invent Drugs and Drugs Save Lives.
Weaver DF. Weaver DF. ChemMedChem. 2024 Jun 17;19(12):e202400074. doi: 10.1002/cmdc.202400074. Epub 2024 Apr 14. ChemMedChem. 2024. PMID: 38616345
Nebulized Furosemide for Pulmonary Inflammation in Intubated Patients With COVID-19: A Phase 2 Randomized Controlled Double-Blind Study.
Muscedere J, Maslove DM, Barden CJ, Weaver DF, Boyd JG, Sibley S, Boyd T, Rewa O, Albert M, Roussos M, Norman PA, Day AG. Muscedere J, et al. Among authors: weaver df. Crit Care Explor. 2024 Feb 2;6(2):e1045. doi: 10.1097/CCE.0000000000001045. eCollection 2024 Feb. Crit Care Explor. 2024. PMID: 38511126 Free PMC article.
191 results