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Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression.
Mónaco DC, Dilernia DA, Fiore-Gartland A, Yu T, Prince JL, Dennis KK, Qin K, Schaefer M, Claiborne DT, Kilembe W, Tang J, Price MA, Farmer P, Gilmour J, Bansal A, Allen S, Goepfert P, Hunter E. Mónaco DC, et al. Among authors: claiborne dt. J Exp Med. 2016 Sep 19;213(10):2049-63. doi: 10.1084/jem.20151984. Epub 2016 Aug 22. J Exp Med. 2016. PMID: 27551154 Free PMC article.
Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis.
Prince JL, Claiborne DT, Carlson JM, Schaefer M, Yu T, Lahki S, Prentice HA, Yue L, Vishwanathan SA, Kilembe W, Goepfert P, Price MA, Gilmour J, Mulenga J, Farmer P, Derdeyn CA, Tang J, Heckerman D, Kaslow RA, Allen SA, Hunter E. Prince JL, et al. Among authors: claiborne dt. PLoS Pathog. 2012;8(11):e1003041. doi: 10.1371/journal.ppat.1003041. Epub 2012 Nov 29. PLoS Pathog. 2012. PMID: 23209412 Free PMC article. Clinical Trial.
HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck.
Carlson JM, Schaefer M, Monaco DC, Batorsky R, Claiborne DT, Prince J, Deymier MJ, Ende ZS, Klatt NR, DeZiel CE, Lin TH, Peng J, Seese AM, Shapiro R, Frater J, Ndung'u T, Tang J, Goepfert P, Gilmour J, Price MA, Kilembe W, Heckerman D, Goulder PJ, Allen TM, Allen S, Hunter E. Carlson JM, et al. Among authors: claiborne dt. Science. 2014 Jul 11;345(6193):1254031. doi: 10.1126/science.1254031. Epub 2014 Jul 10. Science. 2014. PMID: 25013080 Free PMC article.
Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients.
Yue L, Pfafferott KJ, Baalwa J, Conrod K, Dong CC, Chui C, Rong R, Claiborne DT, Prince JL, Tang J, Ribeiro RM, Cormier E, Hahn BH, Perelson AS, Shaw GM, Karita E, Gilmour J, Goepfert P, Derdeyn CA, Allen SA, Borrow P, Hunter E. Yue L, et al. Among authors: claiborne dt. PLoS Pathog. 2015 Jan 8;11(1):e1004565. doi: 10.1371/journal.ppat.1004565. eCollection 2015 Jan. PLoS Pathog. 2015. PMID: 25569444 Free PMC article.
Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression.
Claiborne DT, Prince JL, Scully E, Macharia G, Micci L, Lawson B, Kopycinski J, Deymier MJ, Vanderford TH, Nganou-Makamdop K, Ende Z, Brooks K, Tang J, Yu T, Lakhi S, Kilembe W, Silvestri G, Douek D, Goepfert PA, Price MA, Allen SA, Paiardini M, Altfeld M, Gilmour J, Hunter E. Claiborne DT, et al. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):E1480-9. doi: 10.1073/pnas.1421607112. Epub 2015 Feb 17. Proc Natl Acad Sci U S A. 2015. PMID: 25730868 Free PMC article.
Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis.
Claiborne DT, Scully EP, Palmer CD, Prince JL, Macharia GN, Kopycinski J, Michelo CM, Wiener HW, Parker R, Nganou-Makamdop K, Douek D, Altfeld M, Gilmour J, Price MA, Tang J, Kilembe W, Allen SA, Hunter E. Claiborne DT, et al. PLoS Pathog. 2019 Aug 26;15(8):e1007981. doi: 10.1371/journal.ppat.1007981. eCollection 2019 Aug. PLoS Pathog. 2019. PMID: 31449552 Free PMC article.
29 results