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106 results

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Page 1
Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes.
Nasrallah R, Fast EM, Solaimani P, Knezevic K, Eliades A, Patel R, Thambyrajah R, Unnikrishnan A, Thoms J, Beck D, Vink CS, Smith A, Wong J, Shepherd M, Kent D, Roychoudhuri R, Paul F, Klippert J, Hammes A, Willnow T, Göttgens B, Dzierzak E, Zon LI, Lacaud G, Kouskoff V, Pimanda JE. Nasrallah R, et al. Among authors: lacaud g. Blood. 2016 Oct 13;128(15):1928-1939. doi: 10.1182/blood-2016-02-697870. Epub 2016 Aug 23. Blood. 2016. PMID: 27554085 Free PMC article.
The EHA Research Roadmap: Normal Hematopoiesis.
Jaffredo T, Balduini A, Bigas A, Bernardi R, Bonnet D, Canque B, Charbord P, Cumano A, Delwel R, Durand C, Fibbe W, Forrester L, de Franceschi L, Ghevaert C, Gjertsen B, Gottgens B, Graf T, Heidenreich O, Hermine O, Higgs D, Kleanthous M, Klump H, Kouskoff V, Krause D, Lacaud G, Celso CL, Martens JHA, Méndez-Ferrer S, Menendez P, Oostendorp R, Philipsen S, Porse B, Raaijmakers M, Robin C, Stunnenberg H, Theilgaard-Mönch K, Touw I, Vainchenker W, Corrons JV, Yvernogeau L, Schuringa JJ. Jaffredo T, et al. Among authors: lacaud g. Hemasphere. 2021 Nov 30;5(12):e669. doi: 10.1097/HS9.0000000000000669. eCollection 2021 Dec. Hemasphere. 2021. PMID: 34853826 Free PMC article. No abstract available.
The small inhibitor WM-1119 effectively targets KAT6A-rearranged AML, but not KMT2A-rearranged AML, despite shared KAT6 genetic dependency.
Sheridan M, Maqbool MA, Largeot A, Clayfield L, Xu J, Moncaut N, Sellers R, Whittle J, Paggetti J, Iqbal M, Aucagne R, Delva L, Baker SM, Lie-A-Ling M, Kouskoff V, Lacaud G. Sheridan M, et al. Among authors: lacaud g. J Hematol Oncol. 2024 Oct 8;17(1):91. doi: 10.1186/s13045-024-01610-0. J Hematol Oncol. 2024. PMID: 39380002 Free PMC article.
IκBα controls dormancy in hematopoietic stem cells via retinoic acid during embryonic development.
Thambyrajah R, Maqueda M, Fadlullah MZ, Proffitt M, Neo WH, Guillén Y, Casado-Pelaez M, Herrero-Molinero P, Brujas C, Castelluccio N, González J, Iglesias A, Marruecos L, Ruiz-Herguido C, Esteller M, Mereu E, Lacaud G, Espinosa L, Bigas A. Thambyrajah R, et al. Among authors: lacaud g. Nat Commun. 2024 Jun 1;15(1):4673. doi: 10.1038/s41467-024-48854-5. Nat Commun. 2024. PMID: 38824124 Free PMC article.
Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate.
Thambyrajah R, Maqueda M, Neo WH, Imbach K, Guillén Y, Grases D, Fadlullah Z, Gambera S, Matteini F, Wang X, Calero-Nieto FJ, Esteller M, Florian MC, Porta E, Benedito R, Göttgens B, Lacaud G, Espinosa L, Bigas A. Thambyrajah R, et al. Among authors: lacaud g. Nat Commun. 2024 Feb 21;15(1):1604. doi: 10.1038/s41467-024-45716-y. Nat Commun. 2024. PMID: 38383534 Free PMC article.
Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells.
Steiner I, Flores-Tellez TDNJ, Mevel R, Ali A, Wang P, Schofield P, Behan C, Forsythe N, Ashton G, Taylor C, Mills IG, Oliveira P, McDade SS, Zaiss DM, Choudhury A, Lacaud G, Baena E. Steiner I, et al. Among authors: lacaud g. Cell Rep. 2023 Apr 25;42(4):112377. doi: 10.1016/j.celrep.2023.112377. Epub 2023 Apr 14. Cell Rep. 2023. PMID: 37060563 Free article.
106 results