Weinstein JJ - Search Results

1

Interplay between hydrophobicity and the positive-inside rule in determining membrane-protein topology.

Elazar A, Weinstein JJ, Prilusky J, Fleishman SJ. Elazar A, et al. Among authors: weinstein jj. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10340-5. doi: 10.1073/pnas.1605888113. Epub 2016 Aug 25. Proc Natl Acad Sci U S A. 2016. PMID: 27562165 Free PMC article.

2

PROSS 2: a new server for the design of stable and highly expressed protein variants.

Weinstein JJ, Goldenzweig A, Hoch S, Fleishman SJ. Weinstein JJ, et al. Bioinformatics. 2021 Apr 9;37(1):123-125. doi: 10.1093/bioinformatics/btaa1071. Bioinformatics. 2021. PMID: 33367682 Free PMC article.

3

Stabilization of the SARS-CoV-2 Receptor Binding Domain by Protein Core Redesign and Deep Mutational Scanning.

Leonard AC, Weinstein JJ, Steiner PJ, Erbse AH, Fleishman SJ, Whitehead TA. Leonard AC, et al. Among authors: weinstein jj. bioRxiv [Preprint]. 2021 Nov 24:2021.11.22.469552. doi: 10.1101/2021.11.22.469552. bioRxiv. 2021. Update in: Protein Eng Des Sel. 2022 Feb 17;35:gzac002. doi: 10.1093/protein/gzac002 PMID: 34845448 Free PMC article. Updated. Preprint.

4

Stable and Functionally Diverse Versatile Peroxidases Designed Directly from Sequences.

Barber-Zucker S, Mindel V, Garcia-Ruiz E, Weinstein JJ, Alcalde M, Fleishman SJ. Barber-Zucker S, et al. Among authors: weinstein jj. J Am Chem Soc. 2022 Mar 2;144(8):3564-3571. doi: 10.1021/jacs.1c12433. Epub 2022 Feb 18. J Am Chem Soc. 2022. PMID: 35179866 Free PMC article.

5

Stabilization of the SARS-CoV-2 receptor binding domain by protein core redesign and deep mutational scanning.

Leonard AC, Weinstein JJ, Steiner PJ, Erbse AH, Fleishman SJ, Whitehead TA. Leonard AC, et al. Among authors: weinstein jj. Protein Eng Des Sel. 2022 Feb 17;35:gzac002. doi: 10.1093/protein/gzac002. Protein Eng Des Sel. 2022. PMID: 35325236 Free PMC article.

6

Computational design and molecular dynamics simulations suggest the mode of substrate binding in ceramide synthases.

Zelnik ID, Mestre B, Weinstein JJ, Dingjan T, Izrailov S, Ben-Dor S, Fleishman SJ, Futerman AH. Zelnik ID, et al. Among authors: weinstein jj. Nat Commun. 2023 Apr 22;14(1):2330. doi: 10.1038/s41467-023-38047-x. Nat Commun. 2023. PMID: 37087500 Free PMC article.

7

One-shot design elevates functional expression levels of a voltage-gated potassium channel.

Weinstein JJ, Saikia C, Karbat I, Goldenzweig A, Reuveny E, Fleishman SJ. Weinstein JJ, et al. Protein Sci. 2024 Jun;33(6):e4995. doi: 10.1002/pro.4995. Protein Sci. 2024. PMID: 38747377 Free PMC article.

8

Mega-scale experimental analysis of protein folding stability in biology and design.

Tsuboyama K, Dauparas J, Chen J, Laine E, Mohseni Behbahani Y, Weinstein JJ, Mangan NM, Ovchinnikov S, Rocklin GJ. Tsuboyama K, et al. Among authors: weinstein jj. Nature. 2023 Aug;620(7973):434-444. doi: 10.1038/s41586-023-06328-6. Epub 2023 Jul 19. Nature. 2023. PMID: 37468638 Free PMC article.

9

Association of Neuromelanin-Sensitive MRI Signal With Lifetime Substance Use in Young Women.

Perlman G, Wengler K, Moeller SJ, Kotov R, Klein DN, Weinstein JJ, Horga G, Abi-Dargham A. Perlman G, et al. Among authors: weinstein jj. Am J Psychiatry. 2024 Nov 1;181(11):997-1005. doi: 10.1176/appi.ajp.20220819. Epub 2024 Oct 9. Am J Psychiatry. 2024. PMID: 39380373

10

Kappa opioid receptor availability predicts severity of anhedonia in schizophrenia.

Slifstein M, Qu W, Gil R, Weinstein JJ, Perlman G, Jaworski-Calara T, Meng J, Hu B, Moeller SJ, Horga G, Abi-Dargham A. Slifstein M, et al. Among authors: weinstein jj. Neuropsychopharmacology. 2024 Dec;49(13):2087-2093. doi: 10.1038/s41386-024-01975-3. Epub 2024 Aug 31. Neuropsychopharmacology. 2024. PMID: 39217267

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