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Conformation and Permeability: Cyclic Hexapeptide Diastereomers.
Ono S, Naylor MR, Townsend CE, Okumura C, Okada O, Lokey RS. Ono S, et al. Among authors: naylor mr. J Chem Inf Model. 2019 Jun 24;59(6):2952-2963. doi: 10.1021/acs.jcim.9b00217. Epub 2019 May 8. J Chem Inf Model. 2019. PMID: 31042375 Free PMC article.
Identifying the Cellular Target of Cordyheptapeptide A and Synthetic Derivatives.
Klein VG, Bray WM, Wang HY, Edmondson Q, Schwochert J, Ono S, Naylor MR, Turmon AC, Faris JH, Okada O, Taunton J, Lokey RS. Klein VG, et al. Among authors: naylor mr. ACS Chem Biol. 2021 Aug 20;16(8):1354-1364. doi: 10.1021/acschembio.1c00094. Epub 2021 Jul 12. ACS Chem Biol. 2021. PMID: 34251165 Free PMC article.
Cyclosporin A: Conformational Complexity and Chameleonicity.
Ono S, Naylor MR, Townsend CE, Okumura C, Okada O, Lee HW, Lokey RS. Ono S, et al. Among authors: naylor mr. J Chem Inf Model. 2021 Nov 22;61(11):5601-5613. doi: 10.1021/acs.jcim.1c00771. Epub 2021 Oct 21. J Chem Inf Model. 2021. PMID: 34672629 Free PMC article.
Amide-to-ester substitution as a stable alternative to N-methylation for increasing membrane permeability in cyclic peptides.
Hosono Y, Uchida S, Shinkai M, Townsend CE, Kelly CN, Naylor MR, Lee HW, Kanamitsu K, Ishii M, Ueki R, Ueda T, Takeuchi K, Sugita M, Akiyama Y, Lokey SR, Morimoto J, Sando S. Hosono Y, et al. Among authors: naylor mr. Nat Commun. 2023 Mar 17;14(1):1416. doi: 10.1038/s41467-023-36978-z. Nat Commun. 2023. PMID: 36932083 Free PMC article.
30 results