Zhou W - Search Results

1

Predictive Performance of Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling of Renally Cleared Drugs in Children.

Zhou W, Johnson TN, Xu H, Cheung S, Bui KH, Li J, Al-Huniti N, Zhou D. Zhou W, et al. Among authors: zhou d. CPT Pharmacometrics Syst Pharmacol. 2016 Sep;5(9):475-83. doi: 10.1002/psp4.12101. Epub 2016 Aug 27. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27566992 Free PMC article.

2

Evaluation of Aztreonam Dosing Regimens in Patients With Normal and Impaired Renal Function: A Population Pharmacokinetic Modeling and Monte Carlo Simulation Analysis.

Xu H, Zhou W, Zhou D, Li J, Al-Huniti N. Xu H, et al. Among authors: zhou d, zhou w. J Clin Pharmacol. 2017 Mar;57(3):336-344. doi: 10.1002/jcph.810. Epub 2016 Sep 14. J Clin Pharmacol. 2017. PMID: 27530649

3

Development of a physiologically based pharmacokinetic model to predict the effects of flavin-containing monooxygenase 3 (FMO3) polymorphisms on itopride exposure.

Zhou W, Humphries H, Neuhoff S, Gardner I, Masson E, Al-Huniti N, Zhou D. Zhou W, et al. Among authors: zhou d. Biopharm Drug Dispos. 2017 Sep;38(6):389-393. doi: 10.1002/bdd.2074. Epub 2017 May 28. Biopharm Drug Dispos. 2017. PMID: 28255999

4

Population Pharmacokinetic Analysis of Zolmitriptan and Its Metabolite in Adults and Adolescents to Support Dose Selection in Children With Migraine.

Zhou W, Li J, Birmingham B, Xu H, Lillieborg S, Zhou D, Al-Huniti N. Zhou W, et al. Among authors: zhou d. J Clin Pharmacol. 2017 Oct;57(10):1258-1267. doi: 10.1002/jcph.935. Epub 2017 Jun 5. J Clin Pharmacol. 2017. PMID: 28581633

5

Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children.

Zhou W, Johnson TN, Bui KH, Cheung SYA, Li J, Xu H, Al-Huniti N, Zhou D. Zhou W, et al. Among authors: zhou d. Clin Pharmacol Ther. 2018 Jul;104(1):188-200. doi: 10.1002/cpt.905. Epub 2017 Nov 20. Clin Pharmacol Ther. 2018. PMID: 29027194

6

Physiologically Based Pharmacokinetic Modeling to Evaluate the Systemic Exposure of Gefitinib in CYP2D6 Ultrarapid Metabolizers and Extensive Metabolizers.

Chen Y, Zhou D, Tang W, Zhou W, Al-Huniti N, Masson E. Chen Y, et al. Among authors: zhou d, zhou w. J Clin Pharmacol. 2018 Apr;58(4):485-493. doi: 10.1002/jcph.1036. Epub 2017 Nov 28. J Clin Pharmacol. 2018. PMID: 29193123 Clinical Trial.

7

Dosing Regimen Prediction and Confirmation With Rivaroxaban for Thromboprophylaxis in Children After the Fontan Procedure: Insights From the Phase III UNIVERSE Study.

Zhu P, Willmann S, Zhou W, Yang H, Michelson AD, McCrindle BW, Li JS, Harris KC, Pina LM, Weber T, Nessel K, Lesko LJ, Kubitza D, Zannikos P. Zhu P, et al. Among authors: zhou w. J Clin Pharmacol. 2022 Feb;62(2):220-231. doi: 10.1002/jcph.1966. Epub 2022 Jan 9. J Clin Pharmacol. 2022. PMID: 34524700 Free PMC article. Clinical Trial.

8

Population Pharmacokinetic Analysis of Decitabine in Pediatric Patients With Acute Myeloid Leukemia.

Zhou W, Parasrampuria DA, Nemat S, Nakahara S, Poggesi I, Massarella J, Zhang L, Appiani C. Zhou W, et al. J Clin Pharmacol. 2019 May;59(5):668-676. doi: 10.1002/jcph.1357. Epub 2018 Dec 11. J Clin Pharmacol. 2019. PMID: 30536675

9

Model-informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease.

Willmann S, Ince I, Ahsman M, Coboeken K, Zhang Y, Thelen K, Kubitza D, Zannikos P, Zhou W, Pina LM, Post T, Lippert J. Willmann S, et al. Among authors: zhou w. CPT Pharmacometrics Syst Pharmacol. 2022 Aug;11(8):1111-1121. doi: 10.1002/psp4.12830. Epub 2022 Jun 14. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35665486 Free PMC article.

10

Utilization of physiologically-based pharmacokinetic model to assess disease-mediated therapeutic protein-disease-drug interaction in immune-mediated inflammatory diseases.

Wang L, Chen Y, Zhou W, Miao X, Zhou H. Wang L, et al. Among authors: zhou h, zhou w. Clin Transl Sci. 2022 Feb;15(2):464-476. doi: 10.1111/cts.13164. Epub 2021 Oct 20. Clin Transl Sci. 2022. PMID: 34581012 Free PMC article.

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