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Page 1
MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response.
Staples CJ, Barone G, Myers KN, Ganesh A, Gibbs-Seymour I, Patil AA, Beveridge RD, Daye C, Beniston R, Maslen S, Ahel I, Skehel JM, Collis SJ. Staples CJ, et al. Among authors: ahel i. Cell Rep. 2016 Sep 6;16(10):2565-2575. doi: 10.1016/j.celrep.2016.07.087. Epub 2016 Aug 25. Cell Rep. 2016. PMID: 27568553 Free PMC article.
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 Macrodomain of SARS-CoV-2.
Gahbauer S, Correy GJ, Schuller M, Ferla MP, Doruk YU, Rachman M, Wu T, Diolaiti M, Wang S, Neitz RJ, Fearon D, Radchenko D, Moroz Y, Irwin JJ, Renslo AR, Taylor JC, Gestwicki JE, von Delft F, Ashworth A, Ahel I, Shoichet BK, Fraser JS. Gahbauer S, et al. Among authors: ahel i. bioRxiv [Preprint]. 2022 Jul 28:2022.06.27.497816. doi: 10.1101/2022.06.27.497816. bioRxiv. 2022. Update in: Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2212931120. doi: 10.1073/pnas.2212931120 PMID: 35794891 Free PMC article. Updated. Preprint.
DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on nucleic acids.
Zhu K, Suskiewicz MJ, Chatrin C, Strømland Ø, Dorsey BW, Aucagne V, Ahel D, Ahel I. Zhu K, et al. Among authors: ahel i, ahel d. Nucleic Acids Res. 2024 Jan 25;52(2):801-815. doi: 10.1093/nar/gkad1119. Nucleic Acids Res. 2024. PMID: 38000390 Free PMC article.
The role of ADP-ribosylation in regulating DNA interstrand crosslink repair.
Gunn AR, Banos-Pinero B, Paschke P, Sanchez-Pulido L, Ariza A, Day J, Emrich M, Leys D, Ponting CP, Ahel I, Lakin ND. Gunn AR, et al. Among authors: ahel i. J Cell Sci. 2016 Oct 15;129(20):3845-3858. doi: 10.1242/jcs.193375. Epub 2016 Sep 1. J Cell Sci. 2016. PMID: 27587838 Free PMC article.
Serine ADP-Ribosylation Depends on HPF1.
Bonfiglio JJ, Fontana P, Zhang Q, Colby T, Gibbs-Seymour I, Atanassov I, Bartlett E, Zaja R, Ahel I, Matic I. Bonfiglio JJ, et al. Among authors: ahel i. Mol Cell. 2017 Mar 2;65(5):932-940.e6. doi: 10.1016/j.molcel.2017.01.003. Epub 2017 Feb 9. Mol Cell. 2017. PMID: 28190768 Free PMC article.
Interplay of Histone Marks with Serine ADP-Ribosylation.
Bartlett E, Bonfiglio JJ, Prokhorova E, Colby T, Zobel F, Ahel I, Matic I. Bartlett E, et al. Among authors: ahel i. Cell Rep. 2018 Sep 25;24(13):3488-3502.e5. doi: 10.1016/j.celrep.2018.08.092. Cell Rep. 2018. PMID: 30257210 Free PMC article.
139 results