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FOXD1-ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells.
Cheng P, Wang J, Waghmare I, Sartini S, Coviello V, Zhang Z, Kim SH, Mohyeldin A, Pavlyukov MS, Minata M, Valentim CL, Chhipa RR, Bhat KP, Dasgupta B, La Motta C, Kango-Singh M, Nakano I. Cheng P, et al. Among authors: sartini s. Cancer Res. 2016 Dec 15;76(24):7219-7230. doi: 10.1158/0008-5472.CAN-15-2860. Epub 2016 Aug 28. Cancer Res. 2016. PMID: 27569208 Free PMC article.
Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer.
Antonelli A, Bocci G, La Motta C, Ferrari SM, Fallahi P, Fioravanti A, Sartini S, Minuto M, Piaggi S, Corti A, Alì G, Berti P, Fontanini G, Danesi R, Da Settimo F, Miccoli P. Antonelli A, et al. Among authors: sartini s. J Clin Endocrinol Metab. 2011 Feb;96(2):E288-96. doi: 10.1210/jc.2010-1905. Epub 2010 Dec 8. J Clin Endocrinol Metab. 2011. PMID: 21147882
Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells.
Bocci G, Fioravanti A, La Motta C, Orlandi P, Canu B, Di Desidero T, Mugnaini L, Sartini S, Cosconati S, Frati R, Antonelli A, Berti P, Miccoli P, Da Settimo F, Danesi R. Bocci G, et al. Among authors: sartini s. Biochem Pharmacol. 2011 Jun 1;81(11):1309-16. doi: 10.1016/j.bcp.2011.03.022. Epub 2011 Apr 1. Biochem Pharmacol. 2011. PMID: 21459081
CLM94, a novel cyclic amide with anti-VEGFR-2 and antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo.
Antonelli A, Bocci G, La Motta C, Ferrari SM, Fallahi P, Ruffilli I, Di Domenicantonio A, Fioravanti A, Sartini S, Minuto M, Piaggi S, Corti A, Alì G, Di Desidero T, Berti P, Fontanini G, Danesi R, Da Settimo F, Miccoli P. Antonelli A, et al. Among authors: sartini s. J Clin Endocrinol Metab. 2012 Apr;97(4):E528-36. doi: 10.1210/jc.2011-1987. Epub 2012 Jan 25. J Clin Endocrinol Metab. 2012. PMID: 22278419
A new approach to control the enigmatic activity of aldose reductase.
Del-Corso A, Balestri F, Di Bugno E, Moschini R, Cappiello M, Sartini S, La-Motta C, Da-Settimo F, Mura U. Del-Corso A, et al. Among authors: sartini s. PLoS One. 2013 Sep 3;8(9):e74076. doi: 10.1371/journal.pone.0074076. eCollection 2013. PLoS One. 2013. PMID: 24019949 Free PMC article.
CLM3, a multitarget tyrosine kinase inhibitor with antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo.
Antonelli A, Bocci G, Fallahi P, La Motta C, Ferrari SM, Mancusi C, Fioravanti A, Di Desidero T, Sartini S, Corti A, Piaggi S, Materazzi G, Spinelli C, Fontanini G, Danesi R, Da Settimo F, Miccoli P. Antonelli A, et al. Among authors: sartini s. J Clin Endocrinol Metab. 2014 Apr;99(4):E572-81. doi: 10.1210/jc.2013-2321. Epub 2014 Jan 1. J Clin Endocrinol Metab. 2014. PMID: 24423321
Structure-based optimization of tyrosine kinase inhibitor CLM3. Design, synthesis, functional evaluation, and molecular modeling studies.
Sartini S, Coviello V, Bruno A, La Pietra V, Marinelli L, Simorini F, Taliani S, Salerno S, Marini AM, Fioravanti A, Orlandi P, Antonelli A, Da Settimo F, Novellino E, Bocci G, La Motta C. Sartini S, et al. J Med Chem. 2014 Feb 27;57(4):1225-35. doi: 10.1021/jm401358b. Epub 2014 Feb 5. J Med Chem. 2014. PMID: 24447248
132 results