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Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8(+) T Cell-Mediated Immunity in Colorectal Cancer.
Bhattacharya N, Yuan R, Prestwood TR, Penny HL, DiMaio MA, Reticker-Flynn NE, Krois CR, Kenkel JA, Pham TD, Carmi Y, Tolentino L, Choi O, Hulett R, Wang J, Winer DA, Napoli JL, Engleman EG. Bhattacharya N, et al. Among authors: engleman eg. Immunity. 2016 Sep 20;45(3):641-655. doi: 10.1016/j.immuni.2016.08.008. Epub 2016 Aug 30. Immunity. 2016. PMID: 27590114 Free PMC article.
Normalization of obesity-associated insulin resistance through immunotherapy.
Winer S, Chan Y, Paltser G, Truong D, Tsui H, Bahrami J, Dorfman R, Wang Y, Zielenski J, Mastronardi F, Maezawa Y, Drucker DJ, Engleman E, Winer D, Dosch HM. Winer S, et al. Nat Med. 2009 Aug;15(8):921-9. doi: 10.1038/nm.2001. Epub 2009 Jul 26. Nat Med. 2009. PMID: 19633657 Free PMC article.
Obesity predisposes to Th17 bias.
Winer S, Paltser G, Chan Y, Tsui H, Engleman E, Winer D, Dosch HM. Winer S, et al. Eur J Immunol. 2009 Sep;39(9):2629-35. doi: 10.1002/eji.200838893. Eur J Immunol. 2009. PMID: 19662632 Free article.
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies.
Winer DA, Winer S, Shen L, Wadia PP, Yantha J, Paltser G, Tsui H, Wu P, Davidson MG, Alonso MN, Leong HX, Glassford A, Caimol M, Kenkel JA, Tedder TF, McLaughlin T, Miklos DB, Dosch HM, Engleman EG. Winer DA, et al. Among authors: engleman eg. Nat Med. 2011 May;17(5):610-7. doi: 10.1038/nm.2353. Epub 2011 Apr 17. Nat Med. 2011. PMID: 21499269 Free PMC article.
Th17 cells induce Th1-polarizing monocyte-derived dendritic cells.
Davidson MG, Alonso MN, Yuan R, Axtell RC, Kenkel JA, Suhoski MM, González JC, Steinman L, Engleman EG. Davidson MG, et al. Among authors: engleman eg. J Immunol. 2013 Aug 1;191(3):1175-87. doi: 10.4049/jimmunol.1203201. Epub 2013 Jun 21. J Immunol. 2013. PMID: 23794631 Free PMC article.
312 results