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A proposal for validation of antibodies.
Uhlen M, Bandrowski A, Carr S, Edwards A, Ellenberg J, Lundberg E, Rimm DL, Rodriguez H, Hiltke T, Snyder M, Yamamoto T. Uhlen M, et al. Among authors: edwards a. Nat Methods. 2016 Oct;13(10):823-7. doi: 10.1038/nmeth.3995. Epub 2016 Sep 5. Nat Methods. 2016. PMID: 27595404 Free PMC article.
Reproducibility: Team up with industry.
Edwards A. Edwards A. Nature. 2016 Mar 17;531(7594):299-301. doi: 10.1038/531299a. Nature. 2016. PMID: 26983524 No abstract available.
Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications.
Ayoubi R, Ryan J, Biddle MS, Alshafie W, Fotouhi M, Bolivar SG, Moleon VR, Eckmann P, Worrall D, McDowell I, Southern K, Reintsch W, Durcan TM, Brown CM, Bandrowski A, Virk HS, Edwards AM, McPherson PS, Laflamme C. Ayoubi R, et al. Among authors: edwards am. bioRxiv [Preprint]. 2023 Aug 17:2023.06.01.543292. doi: 10.1101/2023.06.01.543292. bioRxiv. 2023. Update in: Elife. 2023 Nov 23;12:RP91645. doi: 10.7554/eLife.91645 PMID: 37398479 Free PMC article. Updated. Preprint.
Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications.
Ayoubi R, Ryan J, Biddle MS, Alshafie W, Fotouhi M, Bolivar SG, Ruiz Moleon V, Eckmann P, Worrall D, McDowell I, Southern K, Reintsch W, Durcan TM, Brown C, Bandrowski A, Virk H, Edwards AM, McPherson P, Laflamme C. Ayoubi R, et al. Among authors: edwards am. Elife. 2023 Nov 23;12:RP91645. doi: 10.7554/eLife.91645. Elife. 2023. PMID: 37995198 Free PMC article.
A consensus platform for antibody characterization.
Ayoubi R, Ryan J, Gonzalez Bolivar S, Alende C, Ruiz Moleon V, Fotouhi M, Alqazzaz M, Southern K, Alshafie W, Baker MR, Ball AR Jr, Callahan D, Cooper JA, Crosby K, Harvey KJ, Houston DW, Kumaran R, Rego M, Schofield C, Wu H, Biddle MS, Brown CM, Kahn RA, Bandrowski A, Virk HS, Edwards AM, McPherson PS, Laflamme C. Ayoubi R, et al. Among authors: edwards am. Nat Protoc. 2024 Dec 17. doi: 10.1038/s41596-024-01095-8. Online ahead of print. Nat Protoc. 2024. PMID: 39690206 Review.
Perspective: Science is still too closed.
Edwards A. Edwards A. Nature. 2016 May 12;533(7602):S70. doi: 10.1038/533S70a. Nature. 2016. PMID: 27167397 No abstract available.
A data science roadmap for open science organizations engaged in early-stage drug discovery.
Edfeldt K, Edwards AM, Engkvist O, Günther J, Hartley M, Hulcoop DG, Leach AR, Marsden BD, Menge A, Misquitta L, Müller S, Owen DR, Schütt KT, Skelton N, Steffen A, Tropsha A, Vernet E, Wang Y, Wellnitz J, Willson TM, Clevert DA, Haibe-Kains B, Schiavone LH, Schapira M. Edfeldt K, et al. Among authors: edwards am. Nat Commun. 2024 Jul 5;15(1):5640. doi: 10.1038/s41467-024-49777-x. Nat Commun. 2024. PMID: 38965235 Free PMC article. Review.
A guide to selecting high-performing antibodies for Huntingtin (UniProt ID: P42858) for use in western blot, immunoprecipitation, and immunofluorescence.
Fanti R, Ayoubi R, Alende C, Fotouhi M, González Bolívar S, Chandrasekaran R, Southern K, Edwards AM, Harding RJ, Laflamme C; NeuroSGC/YCharOS/EDDU collaborative group; ABIF consortium. Fanti R, et al. F1000Res. 2024 Aug 13;13:922. doi: 10.12688/f1000research.153670.1. eCollection 2024. F1000Res. 2024. PMID: 39257448 Free PMC article.
A public-private partnership to unlock the untargeted kinome.
Knapp S, Arruda P, Blagg J, Burley S, Drewry DH, Edwards A, Fabbro D, Gillespie P, Gray NS, Kuster B, Lackey KE, Mazzafera P, Tomkinson NC, Willson TM, Workman P, Zuercher WJ. Knapp S, et al. Among authors: edwards a. Nat Chem Biol. 2013 Jan;9(1):3-6. doi: 10.1038/nchembio.1113. Nat Chem Biol. 2013. PMID: 23238671 No abstract available.
4,407 results