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Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.
Ross EA, Naylor AJ, O'Neil JD, Crowley T, Ridley ML, Crowe J, Smallie T, Tang TJ, Turner JD, Norling LV, Dominguez S, Perlman H, Verrills NM, Kollias G, Vitek MP, Filer A, Buckley CD, Dean JL, Clark AR. Ross EA, et al. Ann Rheum Dis. 2017 Mar;76(3):612-619. doi: 10.1136/annrheumdis-2016-209424. Epub 2016 Sep 5. Ann Rheum Dis. 2017. PMID: 27597652 Free PMC article.
Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48.
Clayton SA, Daley KK, MacDonald L, Fernandez-Vizarra E, Bottegoni G, O'Neil JD, Major T, Griffin D, Zhuang Q, Adewoye AB, Woolcock K, Jones SW, Goodyear C, Elmesmari A, Filer A, Tennant DA, Alivernini S, Buckley CD, Pitceathly RDS, Kurowska-Stolarska M, Clark AR. Clayton SA, et al. Among authors: o neil jd. Sci Adv. 2021 Dec 10;7(50):eabl5182. doi: 10.1126/sciadv.abl5182. Epub 2021 Dec 8. Sci Adv. 2021. PMID: 34878835 Free PMC article.
Fibroblasts Derived From Vestibular Schwannoma Express Protumorogenic Markers.
Baruah P, Marshall J, Jones PN, Major T, Pucino V, O'Neil JD, Nefla M, McGettrick H, Monksfield P, Irving R, Buckley CD. Baruah P, et al. Among authors: o neil jd. Otol Neurotol. 2023 Dec 1;44(10):e755-e765. doi: 10.1097/MAO.0000000000004011. Epub 2023 Sep 15. Otol Neurotol. 2023. PMID: 37733967
Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon β.
O'Neil JD, Bolimowska OO, Clayton SA, Tang T, Daley KK, Lara-Reyna S, Warner J, Martin CS, Mahida RY, Hardy RS, Arthur JSC, Clark AR. O'Neil JD, et al. Front Immunol. 2023 Oct 24;14:1190261. doi: 10.3389/fimmu.2023.1190261. eCollection 2023. Front Immunol. 2023. PMID: 37942320 Free PMC article.
101 results