Smallie T - Search Results

1

Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.

Ross EA, Naylor AJ, O'Neil JD, Crowley T, Ridley ML, Crowe J, Smallie T, Tang TJ, Turner JD, Norling LV, Dominguez S, Perlman H, Verrills NM, Kollias G, Vitek MP, Filer A, Buckley CD, Dean JL, Clark AR. Ross EA, et al. Among authors: smallie t. Ann Rheum Dis. 2017 Mar;76(3):612-619. doi: 10.1136/annrheumdis-2016-209424. Epub 2016 Sep 5. Ann Rheum Dis. 2017. PMID: 27597652 Free PMC article.

2

Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis.

Yeo L, Adlard N, Biehl M, Juarez M, Smallie T, Snow M, Buckley CD, Raza K, Filer A, Scheel-Toellner D. Yeo L, et al. Among authors: smallie t. Ann Rheum Dis. 2016 Apr;75(4):763-71. doi: 10.1136/annrheumdis-2014-206921. Epub 2015 Apr 9. Ann Rheum Dis. 2016. PMID: 25858640 Free PMC article.

3

Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide.

Smallie T, Ross EA, Ammit AJ, Cunliffe HE, Tang T, Rosner DR, Ridley ML, Buckley CD, Saklatvala J, Dean JL, Clark AR. Smallie T, et al. J Immunol. 2015 Jul 1;195(1):277-88. doi: 10.4049/jimmunol.1402830. Epub 2015 May 27. J Immunol. 2015. PMID: 26019272 Free PMC article.

4

Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo.

O'Neil JD, Ross EA, Ridley ML, Ding Q, Tang T, Rosner DR, Crowley T, Malhi D, Dean JL, Smallie T, Buckley CD, Clark AR. O'Neil JD, et al. Among authors: smallie t. Mol Cell Biol. 2017 May 16;37(11):e00536-16. doi: 10.1128/MCB.00536-16. Print 2017 Jun 1. Mol Cell Biol. 2017. PMID: 28265004 Free PMC article.

5

Macrophage responses to lipopolysaccharide are modulated by a feedback loop involving prostaglandin E₂, dual specificity phosphatase 1 and tristetraprolin.

Tang T, Scambler TE, Smallie T, Cunliffe HE, Ross EA, Rosner DR, O'Neil JD, Clark AR. Tang T, et al. Among authors: smallie t. Sci Rep. 2017 Jun 28;7(1):4350. doi: 10.1038/s41598-017-04100-1. Sci Rep. 2017. PMID: 28659609 Free PMC article.

6

Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.

Ross EA, Smallie T, Ding Q, O'Neil JD, Cunliffe HE, Tang T, Rosner DR, Klevernic I, Morrice NA, Monaco C, Cunningham AF, Buckley CD, Saklatvala J, Dean JL, Clark AR. Ross EA, et al. Among authors: smallie t. J Immunol. 2015 Jul 1;195(1):265-76. doi: 10.4049/jimmunol.1402826. Epub 2015 May 22. J Immunol. 2015. PMID: 26002976 Free PMC article.

7

IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages.

Smallie T, Ricchetti G, Horwood NJ, Feldmann M, Clark AR, Williams LM. Smallie T, et al. J Exp Med. 2010 Sep 27;207(10):2081-8. doi: 10.1084/jem.20100414. Epub 2010 Aug 30. J Exp Med. 2010. PMID: 20805562 Free PMC article.

8

Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages.

Smolinska MJ, Horwood NJ, Page TH, Smallie T, Foxwell BM. Smolinska MJ, et al. Among authors: smallie t. Mol Immunol. 2008 Feb;45(4):990-1000. doi: 10.1016/j.molimm.2007.07.026. Epub 2007 Sep 17. Mol Immunol. 2008. PMID: 17875324

9

Expression of constitutively active STAT3 can replicate the cytokine-suppressive activity of interleukin-10 in human primary macrophages.

Williams LM, Sarma U, Willets K, Smallie T, Brennan F, Foxwell BM. Williams LM, et al. Among authors: smallie t. J Biol Chem. 2007 Mar 9;282(10):6965-75. doi: 10.1074/jbc.M609101200. Epub 2006 Dec 27. J Biol Chem. 2007. PMID: 17194701 Free article.

10

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses.

Krausgruber T, Blazek K, Smallie T, Alzabin S, Lockstone H, Sahgal N, Hussell T, Feldmann M, Udalova IA. Krausgruber T, et al. Among authors: smallie t. Nat Immunol. 2011 Mar;12(3):231-8. doi: 10.1038/ni.1990. Epub 2011 Jan 16. Nat Immunol. 2011. PMID: 21240265

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