Wade SM - Search Results

1

Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks.

Evelyn CR, Lisabeth EM, Wade SM, Haak AJ, Johnson CN, Lawlor ER, Neubig RR. Evelyn CR, et al. Among authors: wade sm. Microarrays (Basel). 2016 May 28;5(2):13. doi: 10.3390/microarrays5020013. Microarrays (Basel). 2016. PMID: 27600078 Free PMC article.

2

CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling.

Evelyn CR, Wade SM, Wang Q, Wu M, Iñiguez-Lluhí JA, Merajver SD, Neubig RR. Evelyn CR, et al. Among authors: wade sm. Mol Cancer Ther. 2007 Aug;6(8):2249-60. doi: 10.1158/1535-7163.MCT-06-0782. Mol Cancer Ther. 2007. PMID: 17699722

3

Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423.

Evelyn CR, Bell JL, Ryu JG, Wade SM, Kocab A, Harzdorf NL, Showalter HD, Neubig RR, Larsen SD. Evelyn CR, et al. Among authors: wade sm. Bioorg Med Chem Lett. 2010 Jan 15;20(2):665-72. doi: 10.1016/j.bmcl.2009.11.056. Epub 2009 Nov 18. Bioorg Med Chem Lett. 2010. PMID: 19963382 Free PMC article.

4

Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents.

Bell JL, Haak AJ, Wade SM, Kirchhoff PD, Neubig RR, Larsen SD. Bell JL, et al. Among authors: wade sm. Bioorg Med Chem Lett. 2013 Jul 1;23(13):3826-32. doi: 10.1016/j.bmcl.2013.04.080. Epub 2013 May 7. Bioorg Med Chem Lett. 2013. PMID: 23707258 Free PMC article.

5

Design and synthesis of tag-free photoprobes for the identification of the molecular target for CCG-1423, a novel inhibitor of the Rho/MKL1/SRF signaling pathway.

Bell JL, Haak AJ, Wade SM, Sun Y, Neubig RR, Larsen SD. Bell JL, et al. Among authors: wade sm. Beilstein J Org Chem. 2013 May 21;9:966-73. doi: 10.3762/bjoc.9.111. Print 2013. Beilstein J Org Chem. 2013. PMID: 23766813 Free PMC article.

6

Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.

Haak AJ, Appleton KM, Lisabeth EM, Misek SA, Ji Y, Wade SM, Bell JL, Rockwell CE, Airik M, Krook MA, Larsen SD, Verhaegen M, Lawlor ER, Neubig RR. Haak AJ, et al. Among authors: wade sm. Mol Cancer Ther. 2017 Jan;16(1):193-204. doi: 10.1158/1535-7163.MCT-16-0482. Epub 2016 Nov 11. Mol Cancer Ther. 2017. PMID: 27837031 Free PMC article.

7

Gαi2 signaling: friend or foe in cardiac injury and heart failure?

Kaur K, Parra S, Chen R, Charbeneau RA, Wade SM, Jay PY, Neubig RR. Kaur K, et al. Among authors: wade sm. Naunyn Schmiedebergs Arch Pharmacol. 2012 May;385(5):443-53. doi: 10.1007/s00210-011-0705-z. Epub 2012 Mar 14. Naunyn Schmiedebergs Arch Pharmacol. 2012. PMID: 22411356 Free PMC article.

8

Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s).

Brink CB, Wade SM, Neubig RR. Brink CB, et al. Among authors: wade sm. J Pharmacol Exp Ther. 2000 Aug;294(2):539-47. J Pharmacol Exp Ther. 2000. PMID: 10900230

9

A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding.

Zhong H, Wade SM, Woolf PJ, Linderman JJ, Traynor JR, Neubig RR. Zhong H, et al. Among authors: wade sm. J Biol Chem. 2003 Feb 28;278(9):7278-84. doi: 10.1074/jbc.M208819200. Epub 2002 Nov 21. J Biol Chem. 2003. PMID: 12446706 Free article.

10

Capillary electrophoresis assay for G protein-coupled receptor-mediated GTPase activity.

Jameson EE, Pei J, Wade SM, Neubig RR, Milligan G, Kennedy RT. Jameson EE, et al. Among authors: wade sm. Anal Chem. 2007 Feb 1;79(3):1158-63. doi: 10.1021/ac061099g. Anal Chem. 2007. PMID: 17263349

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