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The human milk oligosaccharide 2'-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine.
Good M, Sodhi CP, Yamaguchi Y, Jia H, Lu P, Fulton WB, Martin LY, Prindle T, Nino DF, Zhou Q, Ma C, Ozolek JA, Buck RH, Goehring KC, Hackam DJ. Good M, et al. Among authors: ma c. Br J Nutr. 2016 Oct;116(7):1175-1187. doi: 10.1017/S0007114516002944. Epub 2016 Sep 9. Br J Nutr. 2016. PMID: 27609061 Free PMC article.
Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor.
Good M, Sodhi CP, Egan CE, Afrazi A, Jia H, Yamaguchi Y, Lu P, Branca MF, Ma C, Prindle T Jr, Mielo S, Pompa A, Hodzic Z, Ozolek JA, Hackam DJ. Good M, et al. Among authors: ma c. Mucosal Immunol. 2015 Sep;8(5):1166-79. doi: 10.1038/mi.2015.30. Epub 2015 Apr 22. Mucosal Immunol. 2015. PMID: 25899687 Free PMC article.
A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis.
Neal MD, Sodhi CP, Dyer M, Craig BT, Good M, Jia H, Yazji I, Afrazi A, Richardson WM, Beer-Stolz D, Ma C, Prindle T, Grant Z, Branca MF, Ozolek J, Hackam DJ. Neal MD, et al. Among authors: ma c. J Immunol. 2013 Apr 1;190(7):3541-51. doi: 10.4049/jimmunol.1202264. Epub 2013 Mar 1. J Immunol. 2013. PMID: 23455503 Free PMC article.
Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling.
Yazji I, Sodhi CP, Lee EK, Good M, Egan CE, Afrazi A, Neal MD, Jia H, Lin J, Ma C, Branca MF, Prindle T, Richardson WM, Ozolek J, Billiar TR, Binion DG, Gladwin MT, Hackam DJ. Yazji I, et al. Among authors: ma c. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9451-6. doi: 10.1073/pnas.1219997110. Epub 2013 May 6. Proc Natl Acad Sci U S A. 2013. PMID: 23650378 Free PMC article.
Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium.
Good M, Siggers RH, Sodhi CP, Afrazi A, Alkhudari F, Egan CE, Neal MD, Yazji I, Jia H, Lin J, Branca MF, Ma C, Prindle T, Grant Z, Shah S, Slagle D 2nd, Paredes J, Ozolek J, Gittes GK, Hackam DJ. Good M, et al. Among authors: ma c. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11330-5. doi: 10.1073/pnas.1200856109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733781 Free PMC article.
Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice.
Sodhi CP, Neal MD, Siggers R, Sho S, Ma C, Branca MF, Prindle T Jr, Russo AM, Afrazi A, Good M, Brower-Sinning R, Firek B, Morowitz MJ, Ozolek JA, Gittes GK, Billiar TR, Hackam DJ. Sodhi CP, et al. Among authors: ma c. Gastroenterology. 2012 Sep;143(3):708-718.e5. doi: 10.1053/j.gastro.2012.05.053. Epub 2012 Jul 13. Gastroenterology. 2012. PMID: 22796522 Free PMC article.
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