Luo D - Search Results

1

The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production.

Tay MY, Smith K, Ng IH, Chan KW, Zhao Y, Ooi EE, Lescar J, Luo D, Jans DA, Forwood JK, Vasudevan SG. Tay MY, et al. Among authors: luo d. PLoS Pathog. 2016 Sep 13;12(9):e1005886. doi: 10.1371/journal.ppat.1005886. eCollection 2016 Sep. PLoS Pathog. 2016. PMID: 27622521 Free PMC article.

2

Structure-based mutational analysis of the NS3 helicase from dengue virus.

Sampath A, Xu T, Chao A, Luo D, Lescar J, Vasudevan SG. Sampath A, et al. Among authors: luo d. J Virol. 2006 Jul;80(13):6686-90. doi: 10.1128/JVI.02215-05. J Virol. 2006. PMID: 16775356 Free PMC article.

3

Towards the design of flavivirus helicase/NTPase inhibitors: crystallographic and mutagenesis studies of the dengue virus NS3 helicase catalytic domain.

Xu T, Sampath A, Chao A, Wen D, Nanao M, Luo D, Chene P, Vasudevan SG, Lescar J. Xu T, et al. Among authors: luo d. Novartis Found Symp. 2006;277:87-97; discussion 97-101, 251-3. doi: 10.1002/0470058005.ch7. Novartis Found Symp. 2006. PMID: 17319156

4

Crystal structure of the NS3 protease-helicase from dengue virus.

Luo D, Xu T, Hunke C, Grüber G, Vasudevan SG, Lescar J. Luo D, et al. J Virol. 2008 Jan;82(1):173-83. doi: 10.1128/JVI.01788-07. Epub 2007 Oct 17. J Virol. 2008. PMID: 17942558 Free PMC article.

5

Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target.

Lescar J, Luo D, Xu T, Sampath A, Lim SP, Canard B, Vasudevan SG. Lescar J, et al. Among authors: luo d. Antiviral Res. 2008 Nov;80(2):94-101. doi: 10.1016/j.antiviral.2008.07.001. Epub 2008 Jul 30. Antiviral Res. 2008. PMID: 18674567 Review.

6

Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein.

Luo D, Xu T, Watson RP, Scherer-Becker D, Sampath A, Jahnke W, Yeong SS, Wang CH, Lim SP, Strongin A, Vasudevan SG, Lescar J. Luo D, et al. EMBO J. 2008 Dec 3;27(23):3209-19. doi: 10.1038/emboj.2008.232. Epub 2008 Nov 13. EMBO J. 2008. PMID: 19008861 Free PMC article.

7

Flexibility between the protease and helicase domains of the dengue virus NS3 protein conferred by the linker region and its functional implications.

Luo D, Wei N, Doan DN, Paradkar PN, Chong Y, Davidson AD, Kotaka M, Lescar J, Vasudevan SG. Luo D, et al. J Biol Chem. 2010 Jun 11;285(24):18817-27. doi: 10.1074/jbc.M109.090936. Epub 2010 Apr 7. J Biol Chem. 2010. PMID: 20375022 Free PMC article.

The structure at 3.15 A of the soluble NS3 protein from DENV4 covalently attached to 18 residues of the NS2B cofactor region (NS2B(18)NS3) revealed an elongated molecule with the protease domain abutting subdomains I and II of the helicase (Luo, D., Xu, T., Hunke, C …

The structure at 3.15 A of the soluble NS3 protein from DENV4 covalently attached to 18 residues of the NS2B cofactor region (NS2B(18)NS3) r …

8

Crystal structure of the dengue virus methyltransferase bound to a 5'-capped octameric RNA.

Yap LJ, Luo D, Chung KY, Lim SP, Bodenreider C, Noble C, Shi PY, Lescar J. Yap LJ, et al. Among authors: luo d. PLoS One. 2010 Sep 17;5(9):e12836. doi: 10.1371/journal.pone.0012836. PLoS One. 2010. PMID: 20862256 Free PMC article.

9

The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes.

Ferron F, Li Z, Danek EI, Luo D, Wong Y, Coutard B, Lantez V, Charrel R, Canard B, Walz T, Lescar J. Ferron F, et al. Among authors: luo d. PLoS Pathog. 2011 May;7(5):e1002030. doi: 10.1371/journal.ppat.1002030. Epub 2011 May 12. PLoS Pathog. 2011. PMID: 21589902 Free PMC article.

10

The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication.

Tay MY, Saw WG, Zhao Y, Chan KW, Singh D, Chong Y, Forwood JK, Ooi EE, Grüber G, Lescar J, Luo D, Vasudevan SG. Tay MY, et al. Among authors: luo d. J Biol Chem. 2015 Jan 23;290(4):2379-94. doi: 10.1074/jbc.M114.607341. Epub 2014 Dec 8. J Biol Chem. 2015. PMID: 25488659 Free PMC article.

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