Vasudevan SG - Search Results

1

The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production.

Tay MY, Smith K, Ng IH, Chan KW, Zhao Y, Ooi EE, Lescar J, Luo D, Jans DA, Forwood JK, Vasudevan SG. Tay MY, et al. Among authors: vasudevan sg. PLoS Pathog. 2016 Sep 13;12(9):e1005886. doi: 10.1371/journal.ppat.1005886. eCollection 2016 Sep. PLoS Pathog. 2016. PMID: 27622521 Free PMC article.

2

The 37-amino-acid interdomain of dengue virus NS5 protein contains a functional NLS and inhibitory CK2 site.

Forwood JK, Brooks A, Briggs LJ, Xiao CY, Jans DA, Vasudevan SG. Forwood JK, et al. Among authors: vasudevan sg. Biochem Biophys Res Commun. 1999 Apr 21;257(3):731-7. doi: 10.1006/bbrc.1999.0370. Biochem Biophys Res Commun. 1999. PMID: 10208852

3

A small region of the dengue virus-encoded RNA-dependent RNA polymerase, NS5, confers interaction with both the nuclear transport receptor importin-beta and the viral helicase, NS3.

Johansson M, Brooks AJ, Jans DA, Vasudevan SG. Johansson M, et al. Among authors: vasudevan sg. J Gen Virol. 2001 Apr;82(Pt 4):735-745. doi: 10.1099/0022-1317-82-4-735. J Gen Virol. 2001. PMID: 11257177

4

Characterisation of inter- and intra-molecular interactions of the dengue virus RNA dependent RNA polymerase as potential drug targets.

Vasudevan SG, Johansson M, Brooks AJ, Llewellyn LE, Jans DA. Vasudevan SG, et al. Farmaco. 2001 Jan-Feb;56(1-2):33-6. doi: 10.1016/s0014-827x(01)01014-x. Farmaco. 2001. PMID: 11347963 Review.

5

The interdomain region of dengue NS5 protein that binds to the viral helicase NS3 contains independently functional importin beta 1 and importin alpha/beta-recognized nuclear localization signals.

Brooks AJ, Johansson M, John AV, Xu Y, Jans DA, Vasudevan SG. Brooks AJ, et al. Among authors: vasudevan sg. J Biol Chem. 2002 Sep 27;277(39):36399-407. doi: 10.1074/jbc.M204977200. Epub 2002 Jun 24. J Biol Chem. 2002. PMID: 12105224 Free article.

6

Structure of the Dengue virus helicase/nucleoside triphosphatase catalytic domain at a resolution of 2.4 A.

Xu T, Sampath A, Chao A, Wen D, Nanao M, Chene P, Vasudevan SG, Lescar J. Xu T, et al. Among authors: vasudevan sg. J Virol. 2005 Aug;79(16):10278-88. doi: 10.1128/JVI.79.16.10278-10288.2005. J Virol. 2005. PMID: 16051821 Free PMC article.

7

Structure-based mutational analysis of the NS3 helicase from dengue virus.

Sampath A, Xu T, Chao A, Luo D, Lescar J, Vasudevan SG. Sampath A, et al. Among authors: vasudevan sg. J Virol. 2006 Jul;80(13):6686-90. doi: 10.1128/JVI.02215-05. J Virol. 2006. PMID: 16775356 Free PMC article.

8

A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution.

Yap TL, Chen YL, Xu T, Wen D, Vasudevan SG, Lescar J. Yap TL, et al. Among authors: vasudevan sg. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt 2):78-83. doi: 10.1107/S1744309106055084. Epub 2007 Jan 17. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17277444 Free PMC article.

9

Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution.

Yap TL, Xu T, Chen YL, Malet H, Egloff MP, Canard B, Vasudevan SG, Lescar J. Yap TL, et al. Among authors: vasudevan sg. J Virol. 2007 May;81(9):4753-65. doi: 10.1128/JVI.02283-06. Epub 2007 Feb 14. J Virol. 2007. PMID: 17301146 Free PMC article.

10

Towards the design of flavivirus helicase/NTPase inhibitors: crystallographic and mutagenesis studies of the dengue virus NS3 helicase catalytic domain.

Xu T, Sampath A, Chao A, Wen D, Nanao M, Luo D, Chene P, Vasudevan SG, Lescar J. Xu T, et al. Among authors: vasudevan sg. Novartis Found Symp. 2006;277:87-97; discussion 97-101, 251-3. doi: 10.1002/0470058005.ch7. Novartis Found Symp. 2006. PMID: 17319156

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