Walkley CR - Search Results

1

Loss of ephrinB1 in osteogenic progenitor cells impedes endochondral ossification and compromises bone strength integrity during skeletal development.

Nguyen TM, Arthur A, Paton S, Hemming S, Panagopoulos R, Codrington J, Walkley CR, Zannettino AC, Gronthos S. Nguyen TM, et al. Among authors: walkley cr. Bone. 2016 Dec;93:12-21. doi: 10.1016/j.bone.2016.09.009. Epub 2016 Sep 10. Bone. 2016. PMID: 27622886

2

ADAR1p150 Prevents MDA5 and PKR Activation via Distinct Mechanisms to Avert Fatal Autoinflammation.

Hu SB, Heraud-Farlow J, Sun T, Liang Z, Goradia A, Taylor S, Walkley CR, Li JB. Hu SB, et al. Among authors: walkley cr. bioRxiv [Preprint]. 2023 Jan 25:2023.01.25.525475. doi: 10.1101/2023.01.25.525475. bioRxiv. 2023. Update in: Mol Cell. 2023 Nov 2;83(21):3869-3884.e7. doi: 10.1016/j.molcel.2023.09.018 PMID: 36747811 Free PMC article. Updated. Preprint.

3

Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.

Mutsaers AJ, Ng AJ, Baker EK, Russell MR, Chalk AM, Wall M, Liddicoat BJ, Ho PW, Slavin JL, Goradia A, Martin TJ, Purton LE, Dickins RA, Walkley CR. Mutsaers AJ, et al. Among authors: walkley cr. Bone. 2013 Jul;55(1):166-78. doi: 10.1016/j.bone.2013.02.016. Epub 2013 Feb 26. Bone. 2013. PMID: 23486187

4

Cells of origin in osteosarcoma: mesenchymal stem cells or osteoblast committed cells?

Mutsaers AJ, Walkley CR. Mutsaers AJ, et al. Among authors: walkley cr. Bone. 2014 May;62:56-63. doi: 10.1016/j.bone.2014.02.003. Epub 2014 Feb 14. Bone. 2014. PMID: 24530473 Review.

5

Brief report: the differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation.

Martin SK, Fitter S, Dutta AK, Matthews MP, Walkley CR, Hall MN, Ruegg MA, Gronthos S, Zannettino AC. Martin SK, et al. Among authors: walkley cr. Stem Cells. 2015 Apr;33(4):1359-65. doi: 10.1002/stem.1931. Stem Cells. 2015. PMID: 25537496

6

Wnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcoma.

Baker EK, Taylor S, Gupte A, Chalk AM, Bhattacharya S, Green AC, Martin TJ, Strbenac D, Robinson MD, Purton LE, Walkley CR. Baker EK, et al. Among authors: walkley cr. Bone. 2015 Apr;73:223-32. doi: 10.1016/j.bone.2014.12.063. Epub 2015 Jan 5. Bone. 2015. PMID: 25571841 Free article.

7

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.

Gupte A, Baker EK, Wan SS, Stewart E, Loh A, Shelat AA, Gould CM, Chalk AM, Taylor S, Lackovic K, Karlström Å, Mutsaers AJ, Desai J, Madhamshettiwar PB, Zannettino AC, Burns C, Huang DC, Dyer MA, Simpson KJ, Walkley CR. Gupte A, et al. Among authors: walkley cr. Clin Cancer Res. 2015 Jul 15;21(14):3216-29. doi: 10.1158/1078-0432.CCR-14-3026. Epub 2015 Apr 10. Clin Cancer Res. 2015. PMID: 25862761 Free PMC article.

8

BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells.

Baker EK, Taylor S, Gupte A, Sharp PP, Walia M, Walsh NC, Zannettino AC, Chalk AM, Burns CJ, Walkley CR. Baker EK, et al. Among authors: walkley cr. Sci Rep. 2015 May 6;5:10120. doi: 10.1038/srep10120. Sci Rep. 2015. PMID: 25944566 Free PMC article.

9

Increased miR-155-5p and reduced miR-148a-3p contribute to the suppression of osteosarcoma cell death.

Bhattacharya S, Chalk AM, Ng AJ, Martin TJ, Zannettino AC, Purton LE, Lu J, Baker EK, Walkley CR. Bhattacharya S, et al. Among authors: walkley cr. Oncogene. 2016 Oct 6;35(40):5282-5294. doi: 10.1038/onc.2016.68. Epub 2016 Apr 4. Oncogene. 2016. PMID: 27041566

10

Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.

Walia MK, Ho PM, Taylor S, Ng AJ, Gupte A, Chalk AM, Zannettino AC, Martin TJ, Walkley CR. Walia MK, et al. Among authors: walkley cr. Elife. 2016 Apr 12;5:e13446. doi: 10.7554/eLife.13446. Elife. 2016. PMID: 27070462 Free PMC article.

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