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HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.
Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG. Serrano-Villar S, et al. Among authors: lee sa. PLoS Pathog. 2014 May 15;10(5):e1004078. doi: 10.1371/journal.ppat.1004078. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24831517 Free PMC article. Clinical Trial.
Immunologic profiles distinguish aviremic HIV-infected adults.
Ramirez CM, Sinclair E, Epling L, Lee SA, Jain V, Hsue PY, Hatano H, Conn D, Hecht FM, Martin JN, McCune JM, Deeks SG, Hunt PW. Ramirez CM, et al. Among authors: lee sa. AIDS. 2016 Jun 19;30(10):1553-62. doi: 10.1097/QAD.0000000000001049. AIDS. 2016. PMID: 26854811 Free PMC article.
Reply to Barrett, et al.
Freeman ML, Mudd JC, Shive CL, Younes SA, Panigrahi S, Sieg SF, Lee SA, Hunt PW, Calabrese LH, Gianella S, Rodriguez B, Lederman MM. Freeman ML, et al. Among authors: lee sa. Clin Infect Dis. 2016 Jun 1;62(11):1468-9. doi: 10.1093/cid/ciw152. Epub 2016 Mar 21. Clin Infect Dis. 2016. PMID: 27001803 Free PMC article. No abstract available.
IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection.
Younes SA, Freeman ML, Mudd JC, Shive CL, Reynaldi A, Panigrahi S, Estes JD, Deleage C, Lucero C, Anderson J, Schacker TW, Davenport MP, McCune JM, Hunt PW, Lee SA, Serrano-Villar S, Debernardo RL, Jacobson JM, Canaday DH, Sekaly RP, Rodriguez B, Sieg SF, Lederman MM. Younes SA, et al. Among authors: lee sa. J Clin Invest. 2016 Jul 1;126(7):2745-56. doi: 10.1172/JCI85996. Epub 2016 Jun 20. J Clin Invest. 2016. PMID: 27322062 Free PMC article.
2,036 results