Niwa M - Search Results

1

Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.

Jiang D, Lynch C, Medeiros BC, Liedtke M, Bam R, Tam AB, Yang Z, Alagappan M, Abidi P, Le QT, Giaccia AJ, Denko NC, Niwa M, Koong AC. Jiang D, et al. Among authors: niwa m. Sci Rep. 2016 Sep 16;6:33353. doi: 10.1038/srep33353. Sci Rep. 2016. PMID: 27634301 Free PMC article.

2

Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress.

DuRose JB, Tam AB, Niwa M. DuRose JB, et al. Among authors: niwa m. Mol Biol Cell. 2006 Jul;17(7):3095-107. doi: 10.1091/mbc.e06-01-0055. Epub 2006 May 3. Mol Biol Cell. 2006. PMID: 16672378 Free PMC article.

3

B- and T-cell development both involve activity of the unfolded protein response pathway.

Brunsing R, Omori SA, Weber F, Bicknell A, Friend L, Rickert R, Niwa M. Brunsing R, et al. Among authors: niwa m. J Biol Chem. 2008 Jun 27;283(26):17954-61. doi: 10.1074/jbc.M801395200. Epub 2008 Mar 28. J Biol Chem. 2008. PMID: 18375386 Free article.

4

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma.

Papandreou I, Denko NC, Olson M, Van Melckebeke H, Lust S, Tam A, Solow-Cordero DE, Bouley DM, Offner F, Niwa M, Koong AC. Papandreou I, et al. Among authors: niwa m. Blood. 2011 Jan 27;117(4):1311-4. doi: 10.1182/blood-2010-08-303099. Epub 2010 Nov 16. Blood. 2011. PMID: 21081713 Free PMC article.

5

Attenuation of yeast UPR is essential for survival and is mediated by IRE1 kinase.

Chawla A, Chakrabarti S, Ghosh G, Niwa M. Chawla A, et al. Among authors: niwa m. J Cell Biol. 2011 Apr 4;193(1):41-50. doi: 10.1083/jcb.201008071. Epub 2011 Mar 28. J Cell Biol. 2011. PMID: 21444691 Free PMC article.

6

ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6.

Miller M, Tam AB, Cho JY, Doherty TA, Pham A, Khorram N, Rosenthal P, Mueller JL, Hoffman HM, Suzukawa M, Niwa M, Broide DH. Miller M, et al. Among authors: niwa m. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16648-53. doi: 10.1073/pnas.1204151109. Epub 2012 Sep 24. Proc Natl Acad Sci U S A. 2012. PMID: 23011799 Free PMC article.

7

ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK.

Tam AB, Mercado EL, Hoffmann A, Niwa M. Tam AB, et al. Among authors: niwa m. PLoS One. 2012;7(10):e45078. doi: 10.1371/journal.pone.0045078. Epub 2012 Oct 26. PLoS One. 2012. PMID: 23110043 Free PMC article.

8

ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma.

Miller M, Rosenthal P, Beppu A, Mueller JL, Hoffman HM, Tam AB, Doherty TA, McGeough MD, Pena CA, Suzukawa M, Niwa M, Broide DH. Miller M, et al. Among authors: niwa m. J Immunol. 2014 Apr 15;192(8):3475-87. doi: 10.4049/jimmunol.1303047. Epub 2014 Mar 12. J Immunol. 2014. PMID: 24623133 Free PMC article.

9

Ire1 has distinct catalytic mechanisms for XBP1/HAC1 splicing and RIDD.

Tam AB, Koong AC, Niwa M. Tam AB, et al. Among authors: niwa m. Cell Rep. 2014 Nov 6;9(3):850-8. doi: 10.1016/j.celrep.2014.09.016. Epub 2014 Oct 30. Cell Rep. 2014. PMID: 25437541 Free PMC article.

10

Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases.

Jiang D, Niwa M, Koong AC. Jiang D, et al. Among authors: niwa m. Semin Cancer Biol. 2015 Aug;33:48-56. doi: 10.1016/j.semcancer.2015.04.010. Epub 2015 May 16. Semin Cancer Biol. 2015. PMID: 25986851 Free PMC article. Review.

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