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The external gate of the human and Drosophila serotonin transporters requires a basic/acidic amino acid pair for 3,4-methylenedioxymethamphetamine (MDMA) translocation and the induction of substrate efflux.
Sealover NR, Felts B, Kuntz CP, Jarrard RE, Hockerman GH, Lamb PW, Barker EL, Henry LK. Sealover NR, et al. Among authors: henry lk. Biochem Pharmacol. 2016 Nov 15;120:46-55. doi: 10.1016/j.bcp.2016.09.006. Epub 2016 Sep 13. Biochem Pharmacol. 2016. PMID: 27638414
A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport.
Henry LK, Iwamoto H, Field JR, Kaufmann K, Dawson ES, Jacobs MT, Adams C, Felts B, Zdravkovic I, Armstrong V, Combs S, Solis E Jr, Rudnick G, Noskov SY, DeFelice LJ, Meiler J, Blakely RD. Henry LK, et al. J Biol Chem. 2011 Sep 2;286(35):30823-30836. doi: 10.1074/jbc.M111.250308. Epub 2011 Jul 5. J Biol Chem. 2011. PMID: 21730057 Free PMC article.
Inhibitor mechanisms in the S1 binding site of the dopamine transporter defined by multi-site molecular tethering of photoactive cocaine analogs.
Krout D, Pramod AB, Dahal RA, Tomlinson MJ, Sharma B, Foster JD, Zou MF, Boatang C, Newman AH, Lever JR, Vaughan RA, Henry LK. Krout D, et al. Among authors: henry lk. Biochem Pharmacol. 2017 Oct 15;142:204-215. doi: 10.1016/j.bcp.2017.07.015. Epub 2017 Jul 19. Biochem Pharmacol. 2017. PMID: 28734777 Free PMC article.
Corrigendum to "The external gate of the human and Drosophila serotonin transporters requires a basic/acidic amino acid pair for 3,4-methylenedioxymethamphetamine (MDMA) translocation and the induction of substrate efflux" [Biochem. Pharmacol. 120 (2016) 46-55].
Sealover NR, Felts B, Kuntz CP, Jarrard RE, Hockerman GH, Lamb PW, Barker EL, Henry LK. Sealover NR, et al. Among authors: henry lk. Biochem Pharmacol. 2018 Jan;147:9. doi: 10.1016/j.bcp.2017.11.001. Epub 2017 Nov 28. Biochem Pharmacol. 2018. PMID: 29195124 No abstract available.
38 results