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The Effectiveness of Natural Diarylheptanoids against Trypanosoma cruzi: Cytotoxicity, Ultrastructural Alterations and Molecular Modeling Studies.
Sueth-Santiago V, Moraes JB, Sobral Alves ES, Vannier-Santos MA, Freire-de-Lima CG, Castro RN, Mendes-Silva GP, Del Cistia CN, Magalhães LG, Andricopulo AD, Sant Anna CM, Decoté-Ricardo D, Freire de Lima ME. Sueth-Santiago V, et al. Among authors: andricopulo ad. PLoS One. 2016 Sep 22;11(9):e0162926. doi: 10.1371/journal.pone.0162926. eCollection 2016. PLoS One. 2016. PMID: 27658305 Free PMC article.
DYRK1A Inhibitors and Perspectives for the Treatment of Alzheimer's Disease.
de Souza MM, Cenci AR, Teixeira KF, Machado V, Mendes Schuler MCG, Gonçalves AE, Paula Dalmagro A, André Cazarin C, Gomes Ferreira LL, de Oliveira AS, Andricopulo AD. de Souza MM, et al. Among authors: andricopulo ad. Curr Med Chem. 2023;30(6):669-688. doi: 10.2174/0929867329666220620162018. Curr Med Chem. 2023. PMID: 35726411 Review.
Inhibition of Breast Cancer Cell Migration by Cyclotides Isolated from Pombalia calceolaria.
Pinto MEF, Najas JZG, Magalhães LG, Bobey AF, Mendonça JN, Lopes NP, Leme FM, Teixeira SP, Trovó M, Andricopulo AD, Koehbach J, Gruber CW, Cilli EM, Bolzani VS. Pinto MEF, et al. Among authors: andricopulo ad. J Nat Prod. 2018 May 25;81(5):1203-1208. doi: 10.1021/acs.jnatprod.7b00969. Epub 2018 May 14. J Nat Prod. 2018. PMID: 29757646 Free PMC article.
Recent Advances and Perspectives in Cancer Drug Design.
Magalhaes LG, Ferreira LLG, Andricopulo AD. Magalhaes LG, et al. Among authors: andricopulo ad. An Acad Bras Cienc. 2018 May 14;90(1 Suppl 2):1233-1250. doi: 10.1590/0001-3765201820170823. Print 2018. An Acad Bras Cienc. 2018. PMID: 29768576 Free article. Review.
Discovery of Potent, Reversible, and Competitive Cruzain Inhibitors with Trypanocidal Activity: A Structure-Based Drug Design Approach.
de Souza ML, de Oliveira Rezende Junior C, Ferreira RS, Espinoza Chávez RM, Ferreira LLG, Slafer BW, Magalhães LG, Krogh R, Oliva G, Cruz FC, Dias LC, Andricopulo AD. de Souza ML, et al. Among authors: andricopulo ad. J Chem Inf Model. 2020 Feb 24;60(2):1028-1041. doi: 10.1021/acs.jcim.9b00802. Epub 2019 Dec 11. J Chem Inf Model. 2020. PMID: 31765144
Structure-Based and Molecular Modeling Studies for the Discovery of Cyclic Imides as Reversible Cruzain Inhibitors With Potent Anti-Trypanosoma cruzi Activity.
Ferreira RAA, Pauli I, Sampaio TS, de Souza ML, Ferreira LLG, Magalhães LG, Rezende CO Jr, Ferreira RS, Krogh R, Dias LC, Andricopulo AD. Ferreira RAA, et al. Among authors: andricopulo ad. Front Chem. 2019 Nov 25;7:798. doi: 10.3389/fchem.2019.00798. eCollection 2019. Front Chem. 2019. PMID: 31824926 Free PMC article.
Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With In Vivo Activity and Favorable Pharmacokinetics.
Pauli I, Rezende CO Jr, Slafer BW, Dessoy MA, de Souza ML, Ferreira LLG, Adjanohun ALM, Ferreira RS, Magalhães LG, Krogh R, Michelan-Duarte S, Del Pintor RV, da Silva FBR, Cruz FC, Dias LC, Andricopulo AD. Pauli I, et al. Among authors: andricopulo ad. Front Pharmacol. 2022 Jan 5;12:774069. doi: 10.3389/fphar.2021.774069. eCollection 2021. Front Pharmacol. 2022. PMID: 35069198 Free PMC article.
170 results