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Page 1
Lifting the Differentiation Embargo.
Latif AL, Holyoake TL. Latif AL, et al. Among authors: holyoake tl. Cell. 2016 Sep 22;167(1):45-46. doi: 10.1016/j.cell.2016.08.051. Cell. 2016. PMID: 27662083 Free article.
A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease.
Horne GA, Stobo J, Kelly C, Mukhopadhyay A, Latif AL, Dixon-Hughes J, McMahon L, Cony-Makhoul P, Byrne J, Smith G, Koschmieder S, BrÜmmendorf TH, Schafhausen P, Gallipoli P, Thomson F, Cong W, Clark RE, Milojkovic D, Helgason GV, Foroni L, Nicolini FE, Holyoake TL, Copland M. Horne GA, et al. Among authors: holyoake tl. Leukemia. 2020 Jul;34(7):1775-1786. doi: 10.1038/s41375-019-0700-9. Epub 2020 Jan 10. Leukemia. 2020. PMID: 31925317 Free PMC article. Clinical Trial.
BRD4-mediated repression of p53 is a target for combination therapy in AML.
Latif AL, Newcombe A, Li S, Gilroy K, Robertson NA, Lei X, Stewart HJS, Cole J, Terradas MT, Rishi L, McGarry L, McKeeve C, Reid C, Clark W, Campos J, Kirschner K, Davis A, Lopez J, Sakamaki JI, Morton JP, Ryan KM, Tait SWG, Abraham SA, Holyoake T, Higgins B, Huang X, Blyth K, Copland M, Chevassut TJT, Keeshan K, Adams PD. Latif AL, et al. Nat Commun. 2021 Jan 11;12(1):241. doi: 10.1038/s41467-020-20378-8. Nat Commun. 2021. PMID: 33431824 Free PMC article.
Targeted therapy in haematological malignancies.
Hamilton A, Gallipoli P, Nicholson E, Holyoake TL. Hamilton A, et al. Among authors: holyoake tl. J Pathol. 2010 Mar;220(4):404-18. doi: 10.1002/path.2669. J Pathol. 2010. PMID: 20041451 Review.
Combined bezafibrate and medroxyprogesterone acetate have efficacy without haematological toxicity in elderly and relapsed acute myeloid leukaemia (AML).
Murray JA, Khanim FL, Hayden RE, Craddock CF, Holyoake TL, Jackson N, Lumley M, Bunce CM, Drayson MT. Murray JA, et al. Among authors: holyoake tl. Br J Haematol. 2010 Apr;149(1):65-9. doi: 10.1111/j.1365-2141.2009.08055.x. Epub 2010 Jan 13. Br J Haematol. 2010. PMID: 20067564 Free article. Clinical Trial.
Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.
Vukovic M, Guitart AV, Sepulveda C, Villacreces A, O'Duibhir E, Panagopoulou TI, Ivens A, Menendez-Gonzalez J, Iglesias JM, Allen L, Glykofrydis F, Subramani C, Armesilla-Diaz A, Post AE, Schaak K, Gezer D, So CW, Holyoake TL, Wood A, O'Carroll D, Ratcliffe PJ, Kranc KR. Vukovic M, et al. Among authors: holyoake tl. J Exp Med. 2015 Dec 14;212(13):2223-34. doi: 10.1084/jem.20150452. Epub 2015 Dec 7. J Exp Med. 2015. PMID: 26642852 Free PMC article.
216 results